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Titolo:
Intrauterine insemination before transfer of frozen-thawed embryos may improve the pregnancy rate for couples with unexplained infertility: preliminary results of a randomized prospective study
Autore:
Geva, E; Yovel, I; Lerner-Geva, L; Lessing, JB; Azem, F; Amit, A;
Indirizzi:
Univ Calif San Francisco, Dept Obstet Gynecol & Reprod Sci, Ctr Reprod Sci, San Francisco, CA 94143 USA Univ Calif San Francisco San Francisco CA USA 94143 ancisco, CA 94143 USA Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, Israel Tel Aviv Univ Tel Aviv Israel IL-69978 ac Med, IL-69978 Tel Aviv, Israel Tel Aviv Univ, Sackler Fac Med, Tel Aviv Sourasky Med Ctr, Sara Racine IVFUnit,Lis Matern Hosp, IL-69978 Tel Aviv, Israel Tel Aviv Univ Tel Aviv Israel IL-69978 n Hosp, IL-69978 Tel Aviv, Israel
Titolo Testata:
FERTILITY AND STERILITY
fascicolo: 4, volume: 73, anno: 2000,
pagine: 755 - 760
SICI:
0015-0282(200004)73:4<755:IIBTOF>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN CHORIONIC-GONADOTROPIN; CLOMIPHENE CITRATE; CRYOPRESERVATION; CYCLE; OOCYTES; SUCCESS; IUI;
Keywords:
embryo cryopreservation; frozen-thawed embryo transfer; intrauterine insemination; unexplained infertility;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Geva, E Univ Calif San Francisco, Dept Obstet Gynecol & Reprod Sci, Ctr Reprod Sci, 513 Parnassus Ave,HSW 7695, San Francisco, CA 94143 USA Univ Calif San Francisco 513 Parnassus Ave,HSW 7695 San Francisco CA USA 94143
Citazione:
E. Geva et al., "Intrauterine insemination before transfer of frozen-thawed embryos may improve the pregnancy rate for couples with unexplained infertility: preliminary results of a randomized prospective study", FERT STERIL, 73(4), 2000, pp. 755-760

Abstract

Objective: To evaluate whether a combination of IUI and frozen-thawed embryo transfer (FT-ET) with ovulation induction would improve the PR in couples with unexplained infertility. Design: Prospective. randomized study. Setting: In Vitro Fertilization Unit, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel. Patient(s): Sixty-two patients with unexplained infertility were assigned into two groups. The study group was composed of 32 women (38 cycles) who received ovulation induction followed by IUI and FT-ET. The control group was composed of 30 women (33 cycles) who received ovulation induction followed by FT-ET. Intervention(s): Clomiphene citrate (CC) and hCG, IUI, and FT-ET. Main Outcome Measure(s): Pregnancy rate (PR) per cycle, PR per ET. Result(s): In the study group, the PR per cycle and per ET were 36.8% (14 of 38) and 40.6% (13 of 32), respectively. In the control group, the PR percycle and per ET were 12.1% (4 of 33) and 14.3% (4 of 28), respectively. Statistically significant differences were found between the two groups in the PR per cycle (P = .02) and PR per ET (P = .03). No statistically significant difference was found between the groups for the stage in which the embryos were cryopreserved, the survival cleavage rates after thawing, gradingof thawed embryos, and number of embryos transferred. Conclusion(s): In couples with unexplained infertility, the PR may be improved by combining IUI and FT-ET with ovulation induction. Performing IUI before thawing may prevent treatment cancellation in cycles with no survivingembryos. (C) 2000 by American Society for Reproductive Medicine.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/12/20 alle ore 05:34:25