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Titolo:
E-cadherin at the cell periphery is a determinant of keratinocyte differentiation in vitro
Autore:
Owens, DW; Brunton, VG; Parkinson, EK; Frame, MC;
Indirizzi:
CRC, Beatson Inst Canc Res, Glasgow G61 1BD, Lanark, Scotland CRC GlasgowLanark Scotland G61 1BD es, Glasgow G61 1BD, Lanark, Scotland
Titolo Testata:
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
fascicolo: 2, volume: 269, anno: 2000,
pagine: 369 - 376
SICI:
0006-291X(20000316)269:2<369:EATCPI>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
CULTURED HUMAN KERATINOCYTES; CORNIFIED ENVELOPE FORMATION; TERMINAL DIFFERENTIATION; INTEGRIN EXPRESSION; ADHESION MOLECULES; HUMAN EPIDERMIS; CARCINOMAS; FIBRONECTIN; PHOSPHORYLATION; INVOLUCRIN;
Keywords:
cadherins; keratinocyte; differentiation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
31
Recensione:
Indirizzi per estratti:
Indirizzo: Frame, MC CRC, Beatson Inst Canc Res, Garscube Estate,Switchback Rd, Glasgow G61 1BD, Lanark, Scotland CRC Garscube Estate,Switchback Rd Glasgow Lanark Scotland G61 1BD
Citazione:
D.W. Owens et al., "E-cadherin at the cell periphery is a determinant of keratinocyte differentiation in vitro", BIOC BIOP R, 269(2), 2000, pp. 369-376

Abstract

The origin of the signal for keratinocyte differentiation is still unknown. Here, we show that Ca2+- and density-induced translocation of E-cadherin,but not P-cadherin, is accompanied by induction of differentiation-specific proteins in cultured keratinocytes. Antibodies that artificially cluster cell-surface E-cadherin in low extracellular Ca2+ also induce differentiation-specific proteins, implicating E-cadherin as a determinant of keratinocyte differentiation in vitro. (C) 2000 Academic Press.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/09/20 alle ore 13:34:10