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Titolo:
Spontaneous activity in the statoacoustic ganglion of the chicken embryo
Autore:
Jones, TA; Jones, SM;
Indirizzi:
Univ Missouri, Sch Med, Dept Surg Otolaryngol, Columbia, MO 65212 USA UnivMissouri Columbia MO USA 65212 g Otolaryngol, Columbia, MO 65212 USA Univ Missouri, Sch Med, Dept Physiol, Columbia, MO 65212 USA Univ Missouri Columbia MO USA 65212 Dept Physiol, Columbia, MO 65212 USA
Titolo Testata:
JOURNAL OF NEUROPHYSIOLOGY
fascicolo: 3, volume: 83, anno: 2000,
pagine: 1452 - 1468
SICI:
0022-3077(200003)83:3<1452:SAITSG>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
AUDITORY-NERVE FIBERS; INFRASOUND SENSITIVE NEURONS; INNERVATING OTOLITH ORGANS; COCHLEAR GANGLION; HAIR-CELLS; POSTNATAL-DEVELOPMENT; DISCHARGE PATTERNS; PRIMARY AFFERENTS; SQUIRREL-MONKEY; BASILAR PAPILLA;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
104
Recensione:
Indirizzi per estratti:
Indirizzo: Jones, TA Univ Missouri, Sch Med, Dept Surg ENT, 207 Allton Bldg,DC375-00,Columbia,MO 65212 USA Univ Missouri 207 Allton Bldg,DC375-00 Columbia MO USA 65212 USA
Citazione:
T.A. Jones e S.M. Jones, "Spontaneous activity in the statoacoustic ganglion of the chicken embryo", J NEUROPHYS, 83(3), 2000, pp. 1452-1468

Abstract

Spontaneous activity in the statoacoustic ganglion of the chicken embryo. J. Neurophysiol. 83: 1452-1468, 2000. Statoacoustic ganglion cells in the mature bird include neurons that are responsive to sound (auditory) and those that are not (nonauditory). Those that are nonauditory have been shown toinnervate an otolith organ, the macula lagena, whereas auditory neurons innervate the basilar papilla. In the present study, single-unit recordings of statoacoustic ganglion cells were made in embryonic (E19, mean = 19.2 days of incubation) and hatchling (P6-P14, mean = 8.6 days posthatch) chickens. Spontaneous activity from the two age groups was compared with developmental changes. Activity was evaluated for 47 auditory, 11 nonauditory, and 6 undefined eighth nerve neurons in embryos and 29 auditory, 26 nonauditoly, and 1 undefined neurons in hatchlings. For auditory neurons, spontaneous activity displayed an irregular pattern [discharge interval coefficient of variation (CV) was >0.5, mean CV for embryos was 1.46 +/- 0.58 and for hatchlings was 1.02 +/- 0.25; means +/- SD]. Embryonic discharge rates ranged from 0.05 to 97.6 spikes per second (sp/s) for all neurons (mean 18.6 +/- 16.9sp/s). Hatchling spontaneous rates ranged from 1.2 to 185.2 sp/s (mean 66.5 +/- 39.6 sp/s). Discharge rates were significantly higher for hatchlings (P < 0.001). Many embryonic auditory neurons displayed long silent periods between irregular bursts of neural activity, a feature not seen posthatch. All regular bursting discharge patterns were correlated with heart rate in both embryos and hatchlings. Preferred intervals were visible in the time interval histograms (TIHs) of only one embryonic neuron in contrast to 55% of the neurons in posthatch animals. Generally, the embryonic auditory TIH displayed a modified quasi-Poisson distribution. Nonauditory units generallydisplayed regular (CV <0.5) or irregular (CV >0.5) activity and Gaussian and modified-Gaussian TIHs. Long silent periods or bursting patterns were not a characteristic of embryonic nonauditory neurons. CV varied systematically as a function of discharge race in nonauditoly but not auditory primary afferents. Minimum spike intervals (dead time) and interval modes for auditory neurons were longer in embryos (dead time: embryos 2.88 +/- 6.85 ms; hatchlings 1.50 +/- 1.76 ms; modal intervals: embryo 10.09 +/- 22.50 ms, hatching 3.54 +/- 3.29 ms). The results show that significant developmental changes occur in spontaneous activity between E19 and posthatch. It is likely that both presynaptic and postsynaptic changes in the neuroepithelium contribute to maturational refinements during this period of development.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 22:53:19