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Titolo:
EVALUATION OF ERYTHROCYTE HYPERAGGREGATION IN FETAL BLOOD DRAWN BY CORDOCENTESIS AS A MARKER OF FETAL DISEASES
Autore:
BRUN JF; ELBOUHMADI A; BOULOT P; ROUSSEAU O; LAFFARGUE F; VIALA JL; ORSETTI A;
Indirizzi:
COMPLEXE HOSP LAPEYRONE & ARNAUD VILLENEUVE,SERV EXPLORAT PHYSIOL HORMONES & METAB F-34059 MONTPELLIER FRANCE COMPLEX HOSP LAPEYRONIE & ARNAUD VILLENEUVE,SERV GYNECOL OBSTET F-34059 MONTPELLIER FRANCE
Titolo Testata:
Clinical hemorheology
fascicolo: 5, volume: 14, anno: 1994,
pagine: 637 - 642
SICI:
0271-5198(1994)14:5<637:EOEHIF>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Keywords:
FETAL BLOOD; CORDOCENTESIS; HEMORHEOLOGY; ERYTHROCYTE DEFORMABILITY; BLOOD VISCOSITY; ERYTHROCYTE AGGREGATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
15
Recensione:
Indirizzi per estratti:
Citazione:
J.F. Brun et al., "EVALUATION OF ERYTHROCYTE HYPERAGGREGATION IN FETAL BLOOD DRAWN BY CORDOCENTESIS AS A MARKER OF FETAL DISEASES", Clinical hemorheology, 14(5), 1994, pp. 637-642

Abstract

Fetal blood can now be routinely studied by intrauterine sampling. Law erythrocyte aggregability is one of its most prominent hemorheological characteristics before 32 wk gestation. We investigated whether increased RBC aggregability is a marker of fetal pathologies. After we established in 119 fetuses a control group for fetal blood theology, we measured erythrocyte aggregation with the Myrenne apparatus (i.e. a micromethod using 1 droplet of blood) in ill fetuses explored for various diseases. RBC aggregation was increased (>2 Sd for gestational age) in 24 fetal blood samples, with the following diseases: 12.5% toxoplasmosis; 12.5% rhesus immunization; 8.33% autoimmune thrombocytopenia; 8.33% kidney polycystosis; 8.33% old maternal age; 8.33% heart malformation; 8.33% fetal hypotrophia. in autoimmune diseases (rhesus; thrombocytopenia) RBC aggregation was increased in 5/10 cases (50%); in heartor kidney malformations 5/10 (50%); in toxoplasmosis seroconversion 3/23 i.e. 13% of the fetuses had increased aggregation. These data suggest that RBC aggregation is increased in several fetal diseases and may be a nonspecific marker of them.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 17:53:26