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Titolo:
Ovarian hyperstimulation syndrome
Autore:
McElhinney, B; McClure, N;
Indirizzi:
Inst Clin Sci, Dept Obstet & Gynaecol, Belfast, Antrim, North Ireland InstClin Sci Belfast Antrim North Ireland elfast, Antrim, North Ireland
Titolo Testata:
BEST PRACTICE & RESEARCH IN CLINICAL OBSTETRICS & GYNAECOLOGY
fascicolo: 1, volume: 14, anno: 2000,
pagine: 103 - 122
SICI:
1521-6934(200002)14:1<103:OHS>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
ENDOTHELIAL GROWTH-FACTOR; IN-VITRO FERTILIZATION; GONADOTROPIN-RELEASING-HORMONE; HUMAN CHORIONIC-GONADOTROPIN; VASCULAR-PERMEABILITY FACTOR; LUTEAL-PHASE SUPPORT; PLASMA-RENIN ACTIVITY; INVITRO FERTILIZATION; ANGIOTENSIN-II; INTRAVENOUS ALBUMIN;
Keywords:
ovulation induction; ovarian hyperstimulation syndrome; exaggerated folliculogenesis; inflammatory cytokines; capillary permeability; supportive management;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
110
Recensione:
Indirizzi per estratti:
Indirizzo: McElhinney, B Inst Clin Sci, Dept Obstet & Gynaecol, Grosvenor Rd, Belfast, Antrim, North Ireland Inst Clin Sci Grosvenor Rd Belfast Antrim North Ireland and
Citazione:
B. McElhinney e N. McClure, "Ovarian hyperstimulation syndrome", BEST P R CL, 14(1), 2000, pp. 103-122

Abstract

Ovarian hyperstimulation syndrome is an iatrogenic complication of assisted reproduction. In its most severe form, it is potentially fatal. The majorclinical components are marked ovarian enlargement and increased capillarypermeability leading to ascites, hydrothorax and pericardial effusion. Severe cases are associated with thromboembolic phenomena, respiratory distress and renal failure. The definitive pathophysiology is unknown. The available evidence would support a central role for inflammatory cytokines and angiogenic growth factors. Ultrasound examination and serum oestradiol values are currently used to predict patients at risk. The ideal treatment is prevention, but there has been only limited success. The main aims of treatmentare to correct fluid imbalance, maintain renal perfusion and support the patient until the condition resolves. Drug therapy has a limited role, although anticytokine agents may prove useful.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/07/20 alle ore 15:00:54