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Titolo:
Healing of autogenous intramembranous bone in the presence and absence of homologous demineralized intramembranous bone
Autore:
Rabie, ABM; Chay, SH; Wong, AMK;
Indirizzi:
Univ Hong Kong, Fac Dent, Hong Kong, Hong Kong, Peoples R China Univ Hong Kong Hong Kong Hong Kong Peoples R China Kong, Peoples R China
Titolo Testata:
AMERICAN JOURNAL OF ORTHODONTICS AND DENTOFACIAL ORTHOPEDICS
fascicolo: 3, volume: 117, anno: 2000,
pagine: 288 - 297
SICI:
0889-5406(200003)117:3<288:HOAIBI>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
MORPHOGENETIC PROTEIN; INDUCED OSTEOGENESIS; MATRIX; DEFECTS; PROPERTY; REPAIR; GRAFTS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Rabie, ABM Prince Philip Dent Hosp, 34 Hosp Rd, Hong Kong, Hong Kong, Peoples R China Prince Philip Dent Hosp 34 Hosp Rd Hong Kong Hong Kong Peoples R China
Citazione:
A.B.M. Rabie et al., "Healing of autogenous intramembranous bone in the presence and absence of homologous demineralized intramembranous bone", AM J ORTHOD, 117(3), 2000, pp. 288-297

Abstract

This study was designed to examine the osteogenecity of demineralized bonematrix (DBM) prepared from intramembranous (IM) bone and to quantitativelyassess the amount of new bone formed by IM autogenous bone grafts with or without DBMIM. Forty-two defects were created in 42 New Zealand White rabbits. Twenty-one defects were grafted with IM bone alone, and the other 21 defects were grafted with composite IM-DBMIM. Eleven rabbits, 22 defects wereused as controls, where 11 defects were left empty (passive control) and the other 11 defects were filled with rabbit skin collagen (active control). Tissues were retrieved on days 1, 2, 3, 4, 5, 6, 7, and 14 for qualitativeand quantitative analysis. Cells involved in the healing of composite IM and IM-DBMIM bone grafts were identified. No cartilage cells were detected during the healing of either grafts. Appearance of small blood vessels into the newly formed matrix was seen on day 5 in IM bone grafts and on day 4 incomposite IM-DBMIM bone graft. Quantitative analysis was performed by means of image analysis on 100 sections of tissues retrieved after 14 days. Approximately 204% more new bone was formed in defects grafted with composite IM-DBMIM than in those grafted with IM bone alone (P < .0001). No bone was formed across the defects in either active or passive controls. In conclusion, DBMIM significantly increases the osteogenicity of IM bone grafts.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 15:00:03