Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Extracellular matrix-induced signaling in Entamoeba histolytica: Its role in invasiveness
Autore:
Meza, I;
Indirizzi:
Inst Politecn Nacl, CINVESTAV, Dept Biomed Mol, Mexico City 07000, DF, Mexico Inst Politecn Nacl Mexico City DF Mexico 07000 ico City 07000, DF, Mexico
Titolo Testata:
PARASITOLOGY TODAY
fascicolo: 1, volume: 16, anno: 2000,
pagine: 23 - 28
SICI:
0169-4758(200001)16:1<23:EMSIEH>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
MOLECULAR-CLONING; ACTIN CYTOSKELETON; BINDING-PROTEINS; FOCAL ADHESION; CELL-SHAPE; FIBRONECTIN; TROPHOZOITES; TRANSDUCTION; GENE; IDENTIFICATION;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
40
Recensione:
Indirizzi per estratti:
Indirizzo: Meza, I Inst Politecn Nacl, CINVESTAV, Dept Biomed Mol, Apartado Postal 14-740, Mexico City 07000, DF, Mexico Inst Politecn Nacl Apartado Postal 14-740 Mexico City DF Mexico 07000
Citazione:
I. Meza, "Extracellular matrix-induced signaling in Entamoeba histolytica: Its role in invasiveness", PARASIT TOD, 16(1), 2000, pp. 23-28

Abstract

Entamoeba histolytica trophozoites can invade the mucosa of the host largeintestine to cause disease. Here, Isaura Meza describes recent work indicating that the trophozoites respond to the binding of extracellular matrix proteins by activating receptor-mediated signal transduction pathways. Activation of phosphokinase C or adenylyl cyclase induces protein phosphorylation, actin gene expression and reorganization of the actin cytoskeleton to form adhesive structures that promote interaction with the substrate and the release of proteases. The release of proteases at the sites of contact, with the subsequent degradation of the substrate and generation of chemotacticpeptides, facilitates locomotion and dissemination of the invading trophozoites.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/21 alle ore 10:05:13