Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Pre beta 1-high-density lipoprotein (pre beta 1-HDL) concentration can change with low-density lipoprotein-cholesterol (LDL-C) concentration independent of cholesteryl ester transfer protein (CETP)
Autore:
Miida, T; Ozaki, K; Murakami, T; Kashiwa, T; Yamadera, T; Tsuda, T; Inano, K; Okada, M;
Indirizzi:
Niigata Univ, Sch Med, Dept Lab Med, Niigata 9518510, Japan Niigata Univ Niigata Japan 9518510 Dept Lab Med, Niigata 9518510, Japan Niigata Univ, Sch Med, Dept Internal Med 1, Niigata 9518510, Japan NiigataUniv Niigata Japan 9518510 nternal Med 1, Niigata 9518510, Japan St Marianna Univ, Sch Med, Inst Med Sci, Kanagawa 2168512, Japan St Marianna Univ Kanagawa Japan 2168512 Med Sci, Kanagawa 2168512, Japan Niigata Univ Hosp, Div Pharm, Niigata 9518520, Japan Niigata Univ Hosp Niigata Japan 9518520 iv Pharm, Niigata 9518520, Japan Kido Hosp, Dept Cardiol, Niigata 9500891, Japan Kido Hosp Niigata Japan 9500891 sp, Dept Cardiol, Niigata 9500891, Japan
Titolo Testata:
CLINICA CHIMICA ACTA
fascicolo: 1-2, volume: 292, anno: 2000,
pagine: 69 - 80
SICI:
0009-8981(20000225)292:1-2<69:PB1L(B>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
APOLIPOPROTEIN-A-I; PRE-BETA; UNESTERIFIED CHOLESTEROL; CELLULAR CHOLESTEROL; HDL-CHOLESTEROL; HUMAN PLASMA; APOA-I; LPA-I; EFFLUX; METABOLISM;
Keywords:
reverse cholesterol transport; apolipoprotein Al; HDL subfraction; hypercholesterolemia;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
35
Recensione:
Indirizzi per estratti:
Indirizzo: Miida, T Niigata Univ, Sch Med, Dept Lab Med, Asahimachi 1-757, Niigata 9518510, Japan Niigata Univ Asahimachi 1-757 Niigata Japan 9518510 18510, Japan
Citazione:
T. Miida et al., "Pre beta 1-high-density lipoprotein (pre beta 1-HDL) concentration can change with low-density lipoprotein-cholesterol (LDL-C) concentration independent of cholesteryl ester transfer protein (CETP)", CLIN CHIM A, 292(1-2), 2000, pp. 69-80

Abstract

To clarify whether pre beta 1-high-density lipoprotein (pre beta 1-HDL) concentration changes with low-density lipoprotein-cholesterol (LDL-C) concentration independent of cholesteryl ester transfer protein (CETP), we determined pre beta 1-HDL concentration by native two-dimensional gel electrophoresis in 58 subjects with normal triglyceride and HDL-cholesterol concentrations. We also measured LDL-C and CETP concentrations. In 17 subjects, a second blood sample was taken 1-6 months after the first. We found that pre beta 1-HDL concentration was positively correlated with LDL-C concentration (r = 0.529, P < 0.0001) and with CETP mass (r = 0.398, P < 0.01). In 17 patients, Delta pre beta 1-HDL was positively correlated with Delta LDL-C (r = 0.635, P < 0.01), but not with Delta CETP mass (r = 0.275). In conclusion, pre beta 1-HDL concentration changes with LDL-C concentration independent of CETP. These results suggest that pre beta 1-HDL concentration may reflectthe balance between several regulatory factors, including LDL-C and CETP concentrations. (C) 2000 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/09/20 alle ore 23:13:47