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Titolo:
CHARACTERIZATION OF RED-BLOOD-CELL AGGREGATE FORMATION USING AN ANALYTICAL MODEL OF THE ULTRASONIC BACKSCATTERING COEFFICIENT
Autore:
SENNAOUI A; BOYNARD M; PAUTOU C;
Indirizzi:
UNIV PARIS 05,LAB BIOPHYS APPL GRPB,UFR BIOMED ST PERES F-75270 PARIS06 FRANCE UNIV PARIS 05,LAB BIOPHYS APPL GRPB,UFR BIOMED ST PERES F-75270 PARIS06 FRANCE
Titolo Testata:
IEEE transactions on biomedical engineering
fascicolo: 7, volume: 44, anno: 1997,
pagine: 585 - 591
SICI:
0018-9294(1997)44:7<585:CORAFU>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
SCATTERING;
Keywords:
ANALYTICAL MODEL; RED BLOOD CELL AGGREGATION; SEDIMENTATION; ULTRASOUND BACKSCATTERING;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
19
Recensione:
Indirizzi per estratti:
Citazione:
A. Sennaoui et al., "CHARACTERIZATION OF RED-BLOOD-CELL AGGREGATE FORMATION USING AN ANALYTICAL MODEL OF THE ULTRASONIC BACKSCATTERING COEFFICIENT", IEEE transactions on biomedical engineering, 44(7), 1997, pp. 585-591

Abstract

Ultrasound backscattering is well adapted to study the red blood cell(RBC) aggregation phenomenon and growth of RBC aggregates since the backscattered ultrasonic intensity depends on the sixth power of the mean radius of the scattering centers when considered as spherical, Thus, small variations of aggregate size induce large variations of the backscattered intensity, From measurements of the ultrasonic backscattering coefficient (ultrasonic backscattering cross section per unit volume of suspension), an analytical model describing its variation versustime, for human aggregated red blood cells in sedimentation, is proposed. Results given by the model allow to define three phases in the phenomenon: 1) a starting phase characterized by a duration t(s); 2) a stationary final phase beginning at time t(f); 3) a growing intermediate phase characterized by its duration t(f) - t(s). The analytical model has been applied to describe RBC aggregation in dextran 70 000 dalton of different concentrations, and at various hematocrits. Knowledge of the durations t(s), t(f) and the maximum slope s of the curve duringthe intermediate phase, determined with the model, allows a means to study RBC aggregate growth.

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Documento generato il 20/09/20 alle ore 04:39:23