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Titolo:
Tourette syndrome, associated conditions and the complexities of treatment
Autore:
Robertson, MM;
Indirizzi:
Univ Coll London, Dept Psychiat & Behav Sci, London W1N 8AA, England Univ Coll London London England W1N 8AA hav Sci, London W1N 8AA, England Natl Hosp Neurol & Neurosurg, London WC1N 3BG, England Natl Hosp Neurol & Neurosurg London England WC1N 3BG n WC1N 3BG, England
Titolo Testata:
BRAIN
, volume: 123, anno: 2000,
parte:, 3
pagine: 425 - 462
SICI:
0006-8950(200003)123:<425:TSACAT>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
OBSESSIVE-COMPULSIVE-DISORDER; ATTENTION-DEFICIT HYPERACTIVITY; NEUROLEPTIC-INDUCED AKATHISIA; PRELIMINARY CLINICAL-EXPERIENCE; AUTOSOMAL-DOMINANT TRANSMISSION; SELF-INJURIOUS-BEHAVIOR; COMORBID TIC DISORDER; LONG-TERM TREATMENT; OPEN-LABEL TRIAL; DOUBLE-BLIND;
Keywords:
Tourette syndrome; clinical phenomenology; psychopathology; treatment;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
465
Recensione:
Indirizzi per estratti:
Indirizzo: Robertson, MM Univ Coll London, Dept Psychiat & Behav Sci, 2nd Floor,Wolfson Bldg,48 Riding House St, London W1N 8AA, England Univ Coll London 2nd Floor,Wolfson Bldg,48 Riding House St London England W1N 8AA
Citazione:
M.M. Robertson, "Tourette syndrome, associated conditions and the complexities of treatment", BRAIN, 123, 2000, pp. 425-462

Abstract

Tourette syndrome (TS) is characterized by multiple motor ties plus one ormore vocal (phonic) ties, which characteristically wax and wane. It can nolonger be considered the rare and bizarre syndrome that it was once thought to be. The concepts surrounding TS, and our understanding of it, are alsobecoming increasingly complex and, in some individuals, TS is now recognized to be associated with a wide variety of associated behaviours and psychopathologies. It is suggested that TS is heterogeneous from a variety of standpoints including clinical presentation and psychopathology, and thus neuropharmacological responses and possibly even aetiological and genetic mechanisms. In this paper, mention is made of recent findings in epidemiology and genetics, highlighting the complexities of the disorder; these have been chosen because findings in both areas have clinical and management implications. The literature on the clinical manifestations, associated behaviours,psychopathology (and/or comorbid conditions) and management, in particular, is reviewed in detail.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 11:03:43