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Titolo:
A randomised control study of partial liquid ventilation after airway lavage with exogenous surfactant in a meconium aspiration syndrome animal model
Autore:
Nakamura, T; Matsuzawa, S; Sugiura, M; Tamura, M;
Indirizzi:
Nagano Childrens Hosp, Div Neonatol, Nagano 3998288, Japan Nagano Childrens Hosp Nagano Japan 3998288 onatol, Nagano 3998288, Japan
Titolo Testata:
ARCHIVES OF DISEASE IN CHILDHOOD
fascicolo: 2, volume: 82, anno: 2000,
pagine: F160 - F162
SICI:
0003-9888(200003)82:2<F160:ARCSOP>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
BRONCHOALVEOLAR LAVAGE; INJURY;
Keywords:
meconium aspiration syndrome; partial liquid ventilation; exogenous surfactant;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
11
Recensione:
Indirizzi per estratti:
Indirizzo: Nakamura, T Nagano Childrens Hosp, Div Neonatol, 3100 Toyoshina, Nagano 3998288, Japan Nagano Childrens Hosp 3100 Toyoshina Nagano Japan 3998288 pan
Citazione:
T. Nakamura et al., "A randomised control study of partial liquid ventilation after airway lavage with exogenous surfactant in a meconium aspiration syndrome animal model", ARCH DIS CH, 82(2), 2000, pp. F160-F162

Abstract

Aims-To test the hypothesis that lavage with exogenous surfactant before partial liquid ventilation in meconium aspiration syndrome (MAS) would improve debris removal, and therefore the effectiveness of partial liquid ventilation. Methods-12 newborn piglets were randomised into 4 groups, partial liquid ventilation or gas ventilation, with and without surfactant lavage. Physiological and blood gas data were compared between groups by analysis of variance. Results-Arterial oxygen pressure (PaO2) was improved in the group treated with surfactant lavage when compared with the group not receiving surfactant. PaO2 in the group receiving surfactant lavage followed by partial liquidventilation was further improved when compared with the group treated withsurfactant lavage followed by gas ventilation and the group receiving partial Liquid ventilation alone. Conclusion-The effectiveness of partial liquid ventilation in MAS might beenhanced by pretreatment with exogenous surfactant bronchial lavage.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 06:44:21