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Titolo:
Interrupter technique versus plethysmography for measurement of respiratory resistance in children with asthma or cystic fibrosis
Autore:
Oswald-Mammosser, M; Charloux, A; Donato, L; Albrech, C; Speich, JP; Lampert, E; Lonsdorfer, J;
Indirizzi:
Hop Univ Strasbourg, Hop Civil, Serv Explorat Fonctionnelles Resp & Exercise, F-67091 Strasbourg, France Hop Univ Strasbourg Strasbourg France F-67091 F-67091 Strasbourg, France Hop Univ Strasbourg, Hop Hautepierre, Serv Pediat, Strasbourg, France Hop Univ Strasbourg Strasbourg France , Serv Pediat, Strasbourg, France
Titolo Testata:
PEDIATRIC PULMONOLOGY
fascicolo: 3, volume: 29, anno: 2000,
pagine: 213 - 220
SICI:
8755-6863(200003)29:3<213:ITVPFM>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
AIRWAY-RESISTANCE; FLOW INTERRUPTION; IMPEDANCE MEASUREMENTS; BODY PLETHYSMOGRAPHY; YOUNG-CHILDREN; OBSTRUCTION; MECHANICS; INFANTS; DEVICE;
Keywords:
respiratory resistance; interrupter technique; body plethysmography; asthma; cystic fibrosis; children;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Oswald-Mammosser, M Hop Univ Strasbourg, Hop Civil, Serv Explorat Fonctionnelles Resp & Exercise, BP 426, F-67091 Strasbourg, France Hop Univ Strasbourg BP 426 Strasbourg France F-67091
Citazione:
M. Oswald-Mammosser et al., "Interrupter technique versus plethysmography for measurement of respiratory resistance in children with asthma or cystic fibrosis", PEDIAT PULM, 29(3), 2000, pp. 213-220

Abstract

The purpose of the present study was to compare measurements of respiratory system resistance by the interrupter method (Rrsint) with those of airwayresistance by plethysmography (Raw) in nonobstructed children with asthma or cystic fibrosis (ratio of forced expiratory volume in 1 sec to vital capacity, FEV1/VC greater than or equal to 80% with a forced expiratory flow rate between 25-75% of forced vital capacity, FEF25-75 greater than or equalto 75% of normal values) and in obstructed children with the same diseases(FEV1/VC <80% and/or FEF25-75 <75% of normal values). Eighty-one children (47 asthmatics and 34 suffering from cystic fibrosis) aged 5-18 years (mean11.2 +/- SD 3.4 years) were included in the study. For the overall group, we observed generally lower values for Raw (4.7 +/-2.8 cmH(2)O.L-1.s) than for Rrsint20 (extrapolation of the mouth pressure during occlusion to 40 ms after interruption) (5.6 +/- 1.7 cmH(2)O.L-1.s) (P < 0.02), or for Rrsint40 (extrapolation of the mouth pressure during occlusion to 60 ms after interruption) (6.6 +/- 2.2 cmH(2)O.L-1.s) (P < 0.001),but there was no difference between Rrsint20 and Raw in the obstructed subgroup. Moreover, we observed a correlation between the difference (Rrsint20- Raw) expressed in percentage of predicted values and the degree of obstruction estimated by FEV1/VC (r = 0.56, P < 0.001). The differences between the specific resistances (sRrsint20 - sRaw, sRrsint40 - sRaw) were also correlated with the severity of the obstruction (r = 0.65, P < 0.001 and r = 0.57, P < 0.001, respectively). We observed also that the tendency to underestimate resistance by Rrsint in obstructed children was not the same in children with asthma and cystic fibrosis. We conclude that the tendency of Rrsint, as measured with our method, to underestimate airway obstruction appears to increase in proportion to the severity of the airway obstruction. Pediatr Pulmonol. 2000; 29:213-220. (C) 2000 Wiley-Liss, Inc.

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Documento generato il 10/04/20 alle ore 02:44:29