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Titolo:
Frequent assimilation of mitochondrial DNA by grasshopper nuclear genomes
Autore:
Bensasson, D; Zhang, DX; Hewitt, GM;
Indirizzi:
Univ E Anglia, Sch Biol Sci, Norwich NR4 7TJ, Norfolk, England Univ E Anglia Norwich Norfolk England NR4 7TJ h NR4 7TJ, Norfolk, England
Titolo Testata:
MOLECULAR BIOLOGY AND EVOLUTION
fascicolo: 3, volume: 17, anno: 2000,
pagine: 406 - 415
SICI:
0737-4038(200003)17:3<406:FAOMDB>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
CONTROL REGION; GENE-TRANSFER; SEQUENCES; PRIMERS; AMPLIFICATION; PHYLOGENIES; PSEUDOGENES; EVOLUTION; PATTERNS; UTILITY;
Keywords:
Acrididae; numtDNA; gene amplification; heteroplasmy; transposition; DNA migration; nuclear copies; horizontal gene transfer; dead-on-arrival sequences;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Hewitt, GM Univ E Anglia, Sch Biol Sci, Norwich NR4 7TJ, Norfolk, England Univ E Anglia Norwich Norfolk England NR4 7TJ Norfolk, England
Citazione:
D. Bensasson et al., "Frequent assimilation of mitochondrial DNA by grasshopper nuclear genomes", MOL BIOL EV, 17(3), 2000, pp. 406-415

Abstract

Multiple copies of mitochondrial-like DNA were found in the brown mountaingrasshopper, Podisma pedestris (Orthoptera: Acrididae), paralogous to COI and ND5 regions. The same was discovered using the ND5 regions of nine other grasshopper species from four separate subfamilies (Podisminae, Calliptaminae, Crytacanthacridinae, and Gomphocerinae). The extra ND5-like sequenceswere shown to be nuclear in the desert locust, Schistocerca gregaria (Cyrtacanthacridinae), and probably so in P. pedestris and an Italopodisma sp. (Podisminae), Eighty-seven different ND5-like nuclear mitochondrial pseudogenes (Numts) were sequenced from 12 grasshopper individuals. Different nuclear mitochondrial pseudogenes, if descended from the same mitochondrial immigrant, will have diverged from each other under no selective constraints because of their loss of functionality. Evidence of selective constraints in the differences between any two Numt sequences (e.g., if most differences are at third positions of codons) implies that they have separate mitochondrial origins. Through pairwise comparisons of pseudogene sequences, it was established that there have been at least 12 separate mtDNA integrations into P. pedestris nuclear genomes. This is the highest reported rate of horizontal transfer between organellar and nuclear genomes within a single animalspecies. The occurrence of numerous mitochondrial pseudogenes in nuclear genomes derived from separate integration events appears to be a common phenomenon among grasshoppers. More than one type of mechanism appears to have been involved in generating the observed grasshopper Numts.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 12:47:58