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Titolo:
Management of nonresponse and intolerance: Switching strategies
Autore:
Fava, M;
Indirizzi:
Massachusetts Gen Hosp, Depress Clin & Res Program, Boston, MA 02114 USA Massachusetts Gen Hosp Boston MA USA 02114 Program, Boston, MA 02114 USA
Titolo Testata:
JOURNAL OF CLINICAL PSYCHIATRY
, volume: 61, anno: 2000, supplemento:, 2
pagine: 10 - 12
SICI:
0160-6689(2000)61:<10:MONAIS>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
MAJOR DEPRESSION; RESISTANT; BUPROPION; DISCONTINUATION; VENLAFAXINE; SERTRALINE; EFFICACY; TRIAL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Clinical Medicine
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Fava, M Massachusetts Gen Hosp, Depress Clin & Res Program, ACC 812,15 Parkman St,Boston, MA 02114 USA Massachusetts Gen Hosp ACC 812,15 Parkman St Boston MA USA 02114 A
Citazione:
M. Fava, "Management of nonresponse and intolerance: Switching strategies", J CLIN PSY, 61, 2000, pp. 10-12

Abstract

Approximately 29% to 46% of depressed patients show only partial or no response to treatment with antidepressants, with intolerance a frequent cause of treatment Failure or discontinuation. Clinicians frequently switch to other antidepressants patients who have failed to tolerate or to respond to antidepressant treatment. The switching strategy involves substitution of another agent for the agent that has either caused intolerable side effects or has failed to induce a response. Fredman and colleagues have recently surveyed 402 psychiatrists from various parts of the country and asked them what steps they would take for patients who fail to respond ro 8 weeks or more of an adequate dose of a selective serotonin reuptake inhibitor (SSRI). interestingly, switching to a non-SSRI agent was the most popular choice indicated by psychiatrists (44% of respondents), with dual-acting agents and bupropion bring the next most commonly chosen agents. Even though there are no controlled trials of switching strategies in the literature to dare, clinicians often choose this course of action. This article will review some of the currently available studies on switching strategics.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/09/20 alle ore 22:51:52