Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Methadone maintenance vs 180-day psychosocially enriched detoxification for treatment of opioid dependence: A randomized controlled trial
Autore:
Sees, KL; Delucchi, KL; Masson, C; Rosen, A; Clark, HW; Robillard, H; Banys, P; Hall, SM;
Indirizzi:
Univ Calif San Francisco, Dept Psychiat, San Francisco, CA 94143 USA Univ Calif San Francisco San Francisco CA USA 94143 ancisco, CA 94143 USA San Francisco Vet Affairs Med Ctr, San Francisco, CA USA San Francisco VetAffairs Med Ctr San Francisco CA USA Francisco, CA USA
Titolo Testata:
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
fascicolo: 10, volume: 283, anno: 2000,
pagine: 1303 - 1310
SICI:
0098-7484(20000308)283:10<1303:MMV1PE>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
DIAGNOSTIC INTERVIEW SCHEDULE; SUBSTANCE-ABUSE TREATMENT; ADDICTION SEVERITY INDEX; FOLLOW-UP; COCAINE ABUSERS; VALIDITY; PHARMACOTHERAPY; PSYCHOTHERAPY; RELIABILITY; SERVICES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Hall, SM Univ Calif San Francisco, Dept Psychiat, 401 Parnassus Ave,Box 0984-TRC, San Francisco, CA 94143 USA Univ Calif San Francisco 401 Parnassus Ave,Box 0984-TRC San Francisco CA USA 94143
Citazione:
K.L. Sees et al., "Methadone maintenance vs 180-day psychosocially enriched detoxification for treatment of opioid dependence: A randomized controlled trial", J AM MED A, 283(10), 2000, pp. 1303-1310

Abstract

Context Despite evidence that methadone maintenance treatment (MMT) is effective for opioid dependence, it remains a controversial therapy because ofits indefinite provision of a dependence-producing medication. Objective To compare outcomes of patients with opioid dependence treated with MMT vs an alternative treatment, psychosocially enriched 180-day methadone-assisted detoxification. Design Randomized controlled trial conducted from May 1995 to April 1999. Setting Research clinic In an established drug treatment service. Patients Of 858 volunteers screened, 179 adults with diagnosed opioid depen dence were randomized into the study, 154 completed 12 weeks of follow-up. Interventions Patients were randomized to MMT (n = 91), which required 2 hours of psychosocial therapy per week during the first 6 months; or detoxification (n = 88), which required 3 hours of psychosocial therapy per week, 14 education sessions, and 1 hour of cocaine group therapy, if appropriate,for 6 months, and 6 months of (non-methadone) aftercare services. Main Outcome Measures Treatment retention, heroin and cocaine abstinence (by self-report and monthly urinalysis), human immunodeficiency virus (HIV) risk behaviors (Risk of AIDS Behavior scale store), and function in 5 problem areas: employment, family, psychiatric, legal,:and alcohol use (Addiction Severity Index), compared by intervention group. Results Methadone maintenance therapy resulted in greater treatment retention (median, 438.5 vs 174.0 days) and lower heroin use rates than did detoxification, Cocaine use was more closely related to study dropout in detoxification than in MMT, Methadone maintenance therapy resulted in a lower rateof drug-related (mean [SD] at 12 months, 2.17 [3.88] vs 3.73 [6.86]) but not sex-related HIV risk behaviors and in a lower severity score for legal status (mean [SD] at 12 months, 0.05 [0.13] vs 0.13 [0.19]). There were no differences between groups in employment or family functioning or alcohol use. In both groups, monthly heroin use rates were 50% or greater, but days of use per month dropped markedly from baseline. Conclusions Our results confirm the usefulness of MMT in reducing heroin use and HIV risk behaviors. Illicit opioid use continued in both groups, butfrequency was reduced. Results do not provide support for diverting resources from MMT into longterm detoxification.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 04:41:41