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Titolo:
Effects of endurance training on selected parameters of immune function inelderly women
Autore:
Fahlman, M; Boardley, D; Flynn, MG; Braun, WA; Lambert, CP; Bouillon, LE;
Indirizzi:
Wayne State Univ, Dept Hlth Phys Educ & Recreat, Detroit, MI 48202 USA Wayne State Univ Detroit MI USA 48202 uc & Recreat, Detroit, MI 48202 USA
Titolo Testata:
GERONTOLOGY
fascicolo: 2, volume: 46, anno: 2000,
pagine: 97 - 104
SICI:
0304-324X(200003/04)46:2<97:EOETOS>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
KILLER-CELL ACTIVITY; MODERATE-INTENSITY EXERCISE; LYMPHOCYTE SUBPOPULATIONS; PHYSICAL-ACTIVITY; CYTO-TOXICITY; RESPONSES; NUMBERS; STATES; WALK;
Keywords:
exercise; elderly; immune function; endurance training;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
37
Recensione:
Indirizzi per estratti:
Indirizzo: Fahlman, M Wayne State Univ, Dept Hlth Phys Educ & Recreat, Matthaei 262, Detroit, MI48202 USA Wayne State Univ Matthaei 262 Detroit MI USA 48202 MI48202 USA
Citazione:
M. Fahlman et al., "Effects of endurance training on selected parameters of immune function inelderly women", GERONTOLOGY, 46(2), 2000, pp. 97-104

Abstract

Background: Immune function decreases with age, rendering the elderly moresusceptible to infection and tumor development. In addition, intense exercise has been shown to decrease immune function in some populations. Few studies have examined the effects of exercise on immune function in the elderly and, to our knowledge, no studies have examined the effects of exercise on a population of active, but nonexercising elderly. Objective: The purposeof this study was to examine the effects of a 10-week endurance training program on selected parameters of immune function in active elderly women. Methods: A total of 29 healthy, active women, aged 70-87, were randomly assigned to either an exercise (76 +/- 5 years, n = 15) or control (77 +/- 6 years, n = 14) group. The exercise group walked 3 days/week at 70% heart ratereserve (HRR). The duration on day 1 was 20 min and it was increased by 5 min each day until subjects were walking for 50 min (week 3). It remained at 50 min for the duration of the study, while controls maintained normal activity. Blood samples were obtained from both groups at rest, and from the exercise group after 20 min of walking at 70% HRR and after 2 h of recovery. Blood samples were collected prior to endurance training and again after 10 weeks of endurance training. Results: There was a significant decrease in 1-mile walk times as well as heart rate at completion of the walk in the exercise group. Natural cell-mediated cytotoxicity (NCMC) was significantlyhigher post-exercise, compared to pre-exercise both before and after training. After training it remained significantly elevated 2 h postexercise. The resting NCMC was significantly decreased in controls at week 10 but not in the exercise group. Conclusion: Ten weeks of endurance training resulted in a significant decrease in both the 1-mile walk time and the post-walk heart rate in the exercisers but not the controls, without resulting in either an acute or chronic suppression of immune function. Further, endurance training may lead to an attenuation of the decrease in cellular immune measures which occurs during the winter, since the control group experienced a decrease in NCMC and the exercisers did not. Copyright (C) 2000 S.Karger AG, Basel.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/07/20 alle ore 07:00:06