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Titolo:
Differential sustained attention/vigilance changes over time in schizophrenics and controls during a degraded stimulus Continuous Performance Test
Autore:
Mass, R; Wolf, K; Wagner, M; Haasen, C;
Indirizzi:
Univ Hamburg, Hosp Eppendorf, Psychiat Clin, D-20246 Hamburg, Germany UnivHamburg Hamburg Germany D-20246 hiat Clin, D-20246 Hamburg, Germany Univ Bonn, D-5300 Bonn, Germany Univ Bonn Bonn Germany D-5300Univ Bonn, D-5300 Bonn, Germany
Titolo Testata:
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
fascicolo: 1, volume: 250, anno: 2000,
pagine: 24 - 30
SICI:
0940-1334(200002)250:1<24:DSACOT>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
VULNERABILITY INDICATORS; SIGNAL-DETECTION; ATTENTION; DEFICITS; SYMPTOMS;
Keywords:
schizophrenia; Continuous Performance Test; decrements of vigilance; sustained attention; neuropsychology;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
36
Recensione:
Indirizzi per estratti:
Indirizzo: Mass, R Univ Hamburg, Hosp Eppendorf, Psychiat Clin, Martinistr 52, D-20246 Hamburg, Germany Univ Hamburg Martinistr 52 Hamburg Germany D-20246 mburg, Germany
Citazione:
R. Mass et al., "Differential sustained attention/vigilance changes over time in schizophrenics and controls during a degraded stimulus Continuous Performance Test", EUR ARCH PS, 250(1), 2000, pp. 24-30

Abstract

The Continuous Performance Test (CPT) is a widely used procedure for sustained attention/vigilance measurement. However, though the key index of vigilance impairment is the decrement of sensitivity over time during the test period, only few studies have examined whether schizophrenics show a largerdrop in CPT performance than do healthy controls. 48 schizophrenic inpatients and 48 controls were investigated with the Munich CPT (480 visual stimuli, 25% target stimuli, one stimulus per second). Stimuli were degraded by randomly inverting 40%, 41%, 42%, or 43% of the pixels. Results were calculated separately for three consecutive trial sections. Additionally, PANSS ratings, medication, and other clinical data were documented. Schizophrenicsshow a vigilance decrement over time, controls show a vigilance increase. Differential vigilance changes were not related to the level of stimulus degradation. Schizophrenics performed worse than controls only at the lowest degradation level. While overall sensitivity correlated negatively with thedose of atypical neuroleptics and benzodiazepines, vigilance shifts over time correlated negatively with the dose of typical neuroleptics. Furthermore, sensitivity was related to the cognitive PANSS syndrome, number of admissions/duration of illness. Differential sensitivity decrements of schizophrenics and controls can be shown if suited CPT procedures are used. The needfor basic research on experimental conditions of the CPT as well as examination of the relationship between sustained attention/vigilance decrements and clinical features of schizophrenia is suggested.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 06:27:37