Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Brainstem and hypothalamic areas involved in respiratory chemoreflexes: a Fos study in adult rats
Autore:
Berquin, P; Bodineau, L; Gros, F; Larnicol, N;
Indirizzi:
Univ Pivardie Jules Verne, Fac Med, CNRS, Lab Neurophysiol,EP 1592, F-80036 Amiens 01, France Univ Pivardie Jules Verne Amiens France 01 92, F-80036 Amiens 01, France
Titolo Testata:
BRAIN RESEARCH
fascicolo: 1-2, volume: 857, anno: 2000,
pagine: 30 - 40
SICI:
0006-8993(20000228)857:1-2<30:BAHAII>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
ROSTRAL VENTROLATERAL MEDULLA; MIDBRAIN PERIAQUEDUCTAL GRAY; CAROTID-SINUS NERVE; C-FOS; PARABRACHIAL NUCLEUS; BARORECEPTOR STIMULATION; PARAVENTRICULAR NUCLEUS; RETROTRAPEZOID NUCLEUS; CAUDAL HYPOTHALAMUS; SENSITIVE NEURONS;
Keywords:
c-fos; hypoxia; hypercapnia; hypothalamus; brainstem; rat; chemoreflex;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
61
Recensione:
Indirizzi per estratti:
Indirizzo: Larnicol, N Univ Pivardie Jules Verne, Fac Med, CNRS, Lab Neurophysiol,EP 1592, 3 Rue Louvels, F-80036 Amiens 01, France Univ Pivardie Jules Verne 3 Rue Louvels Amiens France 01 ance
Citazione:
P. Berquin et al., "Brainstem and hypothalamic areas involved in respiratory chemoreflexes: a Fos study in adult rats", BRAIN RES, 857(1-2), 2000, pp. 30-40

Abstract

The adaptation to hypoxia and hypercapnia requires the activation of several anatomical structures along the neuraxis. In this study, using Fos immunoreactivity, we sought to map neuronal populations involved in chemoreflex networks activated during the responses to moderate hypoxia (O-2, 11%), andhypercapnia (CO, 5%) in the brainstem and the hypothalamus of the rat. In the: medulla, hypoxia elicited marked and significant staining in the nucleus of the solitary tract (NTS), and in parapyramidal neurons located near the ventral surface, whereas hypercapnia evoked significantly c-fos only near the ventral surface in paraolivar neurons. In contrast, within pontine and suprapontine structures, both hypoxia and hypercapnia evoked similarly Fos immunoreactivity in the lateral parabrachialis area, the central grey, the caudal hypothalamus (dorsomedial and posterior hypothalamic nuclei), and in a ventro-lateral hypothalamic area, extending from the rostral limit of the mammillary nuclei to the retrochiasmatic area. more rostrally, labelling was observed in the paraventricular nucleus of the hypothalamus in response to hypercapnia, and in the supraoptic nucleus in response to hypoxia. These results support the hypothesis that chemoreflexes pathways are not onlyrestricted to medulla and pens but also involved mesencephalic and hypothalamic regions. The parabrachialis area and the central grey may be key relays between caudal and ventral hypothalamic neurons, and medullary neurons involved in the response to hypoxia and hypercapnia, (C) 2000 Published by Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/09/20 alle ore 03:26:38