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Titolo:
Anticipatory errors after unilateral lesions of the subthalamic nucleus inthe rat: Evidence for a failure of response inhibition
Autore:
Phillips, JM; Brown, VJ;
Indirizzi:
Univ St Andrews, Sch Psychol, St Andrews KY16 9JU, Fife, Scotland Univ St Andrews St Andrews Fife Scotland KY16 9JU Y16 9JU, Fife, Scotland
Titolo Testata:
BEHAVIORAL NEUROSCIENCE
fascicolo: 1, volume: 114, anno: 2000,
pagine: 150 - 157
SICI:
0735-7044(200002)114:1<150:AEAULO>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
STRIATAL DOPAMINE DEPLETION; BASAL GANGLIA; PARKINSONS-DISEASE; REACTION-TIME; ATTENTION; CIRCUITS; DEFICITS; INDUCE; MODELS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Brown, VJ Univ St Andrews, Sch Psychol, St Andrews KY16 9JU, Fife, Scotland Univ St Andrews St Andrews Fife Scotland KY16 9JU ife, Scotland
Citazione:
J.M. Phillips e V.J. Brown, "Anticipatory errors after unilateral lesions of the subthalamic nucleus inthe rat: Evidence for a failure of response inhibition", BEHAV NEURO, 114(1), 2000, pp. 150-157

Abstract

The nature of anticipatory responding in rats with unilateral subthalamic nucleus lesions was examined. Rats were trained to respond toward visual targets that were preceded by 1 of 4 different cues. For normal rats, a cue invokes an involuntary attentional orienting that enhances processing of thetarget at the location of attention. The cue is also a salient stimulus towhich a response must be suppressed. Therefore, this task was used to investigate possible attentional impairments, as well as the ability of a lesioned rat to suppress competing motor programs. Responding under target control was not affected by the lesion. Then was an increase in anticipatory responses before target onset, which could be accounted for by a failure to inhibit contralateral responses.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 07:08:06