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Titolo:
Small hepatocellular carcinoma: Safety and efficacy of single high-dose percutaneous acetic acid injection for treatment
Autore:
Liang, HL; Yang, CF; Pan, HB; Lai, KH; Cheng, JS; Lo, GH; Chen, CKH; Lai, PH;
Indirizzi:
Kaohsiung Vet Gen Hosp, Dept Radiol, Kaohsiung 813, Taiwan Kaohsiung Vet Gen Hosp Kaohsiung Taiwan 813 adiol, Kaohsiung 813, Taiwan Kaohsiung Vet Gen Hosp, Dept Med, Kaohsiung 813, Taiwan Kaohsiung Vet Gen Hosp Kaohsiung Taiwan 813 t Med, Kaohsiung 813, Taiwan Natl Yang Ming Univ, Dept Radiol, Taipei 112, Taiwan Natl Yang Ming Univ Taipei Taiwan 112 v, Dept Radiol, Taipei 112, Taiwan Natl Yang Ming Univ, Dept Med, Taipei 112, Taiwan Natl Yang Ming Univ Taipei Taiwan 112 Univ, Dept Med, Taipei 112, Taiwan
Titolo Testata:
RADIOLOGY
fascicolo: 3, volume: 214, anno: 2000,
pagine: 769 - 774
SICI:
0033-8419(200003)214:3<769:SHCSAE>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
ETHANOL INJECTION; HEPATIC-TUMORS; THERAPY; LIVER; COMPLICATIONS; EMBOLIZATION; ABLATION;
Keywords:
acetic acid; alcohol ablation; liver, interventional procedures; liver neoplasms; liver neoplasms, CT; liver neoplasms, US;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
28
Recensione:
Indirizzi per estratti:
Indirizzo: Yang, CF Kaohsiung Vet Gen Hosp, Dept Radiol, 386 Ta Chung 1st Rd, Kaohsiung 813, Taiwan Kaohsiung Vet Gen Hosp 386 Ta Chung 1st Rd Kaohsiung Taiwan813
Citazione:
H.L. Liang et al., "Small hepatocellular carcinoma: Safety and efficacy of single high-dose percutaneous acetic acid injection for treatment", RADIOLOGY, 214(3), 2000, pp. 769-774

Abstract

PURPOSE: To evaluate the safety and efficacy of single high-dose percutaneous acetic acid injection (PAI) for treatment of small (<3-cm-diameter) hepatocellular carcinoma (HCC). MATERIALS AND METHODS: Eighteen patients with HCC (22 nodules; diameter range, 1.5-3.0 cm) underwent single PAI. With ultrasonographic or computed tomographic (CT) guidance, 4-11 mt of 50% acetic acid was slowly injected into the center of the nodule through a skinny multiple-side-hole needle. Follow-up was performed with helical contrast material-enhanced CT. Complications of high-dose PAI were recorded. RESULTS: Seventeen nodules showed no local recurrence (follow-up, 6-29 months) after single PAI. At a mean follow-up of 15.6 months, mean tumor diameter was 2.1 cm and mean injected volume was 6.4 mt. Four nodules showed residual tumor (mean tumor diameter, 2.6 cm; mean injected volume, 5.8 mt). The mean ratio of injected to estimated volume of acetic acid was 1.21 in cases of successful single PAI and 0.72 in cases of local recurrence (P < .001). One patient with preexistent right portal venous thrombosis died of hepatic failure 37 days after PAI. Other complications included severe pain (11%), high fever (4%), and segmental wedge infarction (4%). CONCLUSION: Single high-dose PAI is safe and effective for treatment of small HCC.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/07/20 alle ore 12:31:49