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Titolo:
Incidence of cancer among commercial airline pilots
Autore:
Rafnsson, V; Hrafnkelsson, J; Tulinius, H;
Indirizzi:
Univ Iceland, Dept Prevent Med, IS-105 Reykjavik, Iceland Univ Iceland Reykjavik Iceland IS-105 ent Med, IS-105 Reykjavik, Iceland Landspitalinn, Dept Oncol, Reykjavik, Iceland Landspitalinn Reykjavik Iceland italinn, Dept Oncol, Reykjavik, Iceland Iceland Canc Registry, IS-105 Reykjavik, Iceland Iceland Canc Registry Reykjavik Iceland IS-105 IS-105 Reykjavik, Iceland
Titolo Testata:
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
fascicolo: 3, volume: 57, anno: 2000,
pagine: 175 - 179
SICI:
1351-0711(200003)57:3<175:IOCACA>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
NESTED CASE-CONTROL; SOCIOECONOMIC-STATUS; RADIATION EXPOSURE; MALIGNANT-MELANOMA; COSMIC-RADIATION; UNITED-STATES; AIR-FORCE; MORTALITY; RISK; OCCUPATION;
Keywords:
cancer registry; malignant melanoma of the skin; cosmic radiation; block-hours; time zones;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Rafnsson, V Univ Iceland, Dept Prevent Med, Soltun 1, IS-105 Reykjavik, Iceland Univ Iceland Soltun 1 Reykjavik Iceland IS-105 javik, Iceland
Citazione:
V. Rafnsson et al., "Incidence of cancer among commercial airline pilots", OCC ENVIR M, 57(3), 2000, pp. 175-179

Abstract

Objectives-To describe the cancer pattern in a cohort of commercial pilotsby follow up through the Icelandic Cancer Registry. Methods-This is a retrospective cohort study of 458 pilots with emphasis on subcohort working for an airline operating on international routes. A computerised file of the cohort was record linked to the Cancer Registry by making use of personal identification numbers. Expected numbers of cancer cases were calculated on the basis of number of person-years and incidences ofcancer at specific sites for men provided by the Cancer Registry. Numbers of separate analyses were made according to different exposure variables. Results-The standardised incidence ratio (SIR) for all cancers was 0.97 (95% confidence interval (95% CI) 0.62 to 1.46) in the total cohort and 1.16 (95% CI 0.70 to 1.81) among those operating on international routes. The SIR for malignant melanoma of the skin was 10.20, 95% CI 3.29 to 23.81 in thetotal cohort and 15.63, 95% CI 5.04 to 36.46 in the restricted cohort. Analyses according to number of block-hours and radiation dose showed that malignant melanomas were found in the subgroups with highest exposure estimates, the SIRs were 13.04 and 28.57 respectively. The SIR was 25.00 for malignant melanoma among those who had been flying over five time zones,Conclusions-The study shows a high occurrence of malignant melanoma among pilots. It is open to discussion what role exposure of cosmic radiation, numbers of block-hours flown, or lifestyle factors-such as possible excessivesunbathing-play in the aetiology of cancer among pilots. This calls for further and more powerful studies. The excess of malignant melanoma among those flying over five time zones suggests that the importance of disturbance of the circadian rhythm should be taken into consideration in future studies.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/11/20 alle ore 14:29:29