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Titolo:
Factor XII deficiency in women with recurrent miscarriage
Autore:
Yamada, H; Kato, EH; Ebina, Y; Kishida, T; Hoshi, N; Kobashi, G; Sakuragi, N; Fujimoto, S;
Indirizzi:
Hokkaido Univ, Sch Med, Dept Obstet & Gynecol, Kita Ku, Sapporo, Hokkaido 060, Japan Hokkaido Univ Sapporo Hokkaido Japan 060 Ku, Sapporo, Hokkaido 060, Japan Hokkaido Univ, Sch Med, Dept Publ Hlth, Kita Ku, Sapporo, Hokkaido 060, Japan Hokkaido Univ Sapporo Hokkaido Japan 060 Ku, Sapporo, Hokkaido 060, Japan
Titolo Testata:
GYNECOLOGIC AND OBSTETRIC INVESTIGATION
fascicolo: 2, volume: 49, anno: 2000,
pagine: 80 - 83
SICI:
0378-7346(2000)49:2<80:FXDIWW>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
COAGULATION-FACTOR-XII; HEPATOCYTE GROWTH-FACTOR; KILLER-CELL ACTIVITY; FACTOR-V-LEIDEN; MYOCARDIAL-INFARCTION; SPONTANEOUS-ABORTION; FACTOR ACTIVATOR; THROMBOEMBOLISM; GENE; ABNORMALITIES;
Keywords:
coagulation; growth factor; factor XII; pregnancy; recurrent abortions;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
35
Recensione:
Indirizzi per estratti:
Indirizzo: Yamada, H Hokkaido Univ, Sch Med, Dept Obstet & Gynecol, Kita Ku, N15,W7, Sapporo, Hokkaido 060, Japan Hokkaido Univ N15,W7 Sapporo Hokkaido Japan 060 kaido 060, Japan
Citazione:
H. Yamada et al., "Factor XII deficiency in women with recurrent miscarriage", GYNECOL OBS, 49(2), 2000, pp. 80-83

Abstract

Congenital thrombophilia is known to cause significant maternal complications, and possibly has an adverse effect on normal feta I development, The aim of this study was to assess the prevalence of factor XII (FXII) deficiency in women with a history of recurrent miscarriage. Two hundred and forty-one consecutive Japanese women with a history of two or more recurrent miscarriages were prospectively assessed for their etiology by conventional screening methods. Seven women were found to have reduced FXII activity (19.2-46.1%) and prolonged activated partial thromboplastin time (33.3-51.3 s). Of these 7 women, 6 had experienced early pregnancy losses, while 1 woman had experienced repeated midtrimester fetal losses with coincidental gestational thrombocytopenia, In 241 women with a history of recurrent miscarriage,the prevalence of FXII deficiency was 2.9%. Copyright (C) 2000 S. Karger AG, Basel.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 15/07/20 alle ore 08:48:51