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Titolo:
Limited performance of quantitative assessment of myocardial function by thallium-201 gated myocardial single-photon emission tomography
Autore:
Lee, DS; Ahn, JY; Kim, SK; Oh, BH; Seo, JD; Chung, JK; Lee, MC;
Indirizzi:
Seoul Natl Univ, Coll Med, Dept Nucl Med, Seoul 110744, South Korea Seoul Natl Univ Seoul South Korea 110744 Med, Seoul 110744, South Korea Seoul Natl Univ, Coll Med, Dept Internal Med, Seoul 110744, South Korea Seoul Natl Univ Seoul South Korea 110744 Med, Seoul 110744, South Korea Seoul Natl Univ, Med Res Ctr, Inst Heart, Seoul, South Korea Seoul Natl Univ Seoul South Korea s Ctr, Inst Heart, Seoul, South Korea Seoul Natl Univ, Med Res Ctr, Inst Radiat Med, Seoul, South Korea Seoul Natl Univ Seoul South Korea , Inst Radiat Med, Seoul, South Korea
Titolo Testata:
EUROPEAN JOURNAL OF NUCLEAR MEDICINE
fascicolo: 2, volume: 27, anno: 2000,
pagine: 185 - 191
SICI:
0340-6997(200002)27:2<185:LPOQAO>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
VENTRICULAR EJECTION FRACTION; PERFUSION IMAGES; SPECT; AGREEMENT;
Keywords:
thallium-201 gated single-photon emission tomography; quantification; ventricular volume; ejection fraction; reproducibility;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Lee, DS Seoul Natl Univ, Coll Med, Dept Nucl Med, 28 Yungundong Chongnogu,Seoul 110744, South Korea Seoul Natl Univ 28 Yungundong Chongnogu Seoul South Korea 110744
Citazione:
D.S. Lee et al., "Limited performance of quantitative assessment of myocardial function by thallium-201 gated myocardial single-photon emission tomography", EUR J NUCL, 27(2), 2000, pp. 185-191

Abstract

We investigated the reproducibility between thallium-201 and technetium-99m methoxyisobutylisonitrile (MIBI) gated single-photon emission tomography (SPET) for the assessment of indices of myocardial function such as end-diastolic and end-systolic volume (EDV, ESV), ejection fraction (EF) and wall motion. Rest Tl-201 (111 MBq) gated SPET was sequentially performed twice in 20 patients. Rest Tl-201 gated SPET and rest Tc-99m-MIBI (370 MBq) gated SPET were performed 24 h apart in 40 patients. Wall motion was graded usingthe surface display of the Cedars quantitative gated SPET (QGS) software. EDV, ESV and EF were also measured using the QGS software. The reproducibility of functional assessment on rest Tl-201 gated SPET was compared with that on Tc-99m-MIBI gated SPET. and also with that between Tl-201 gated SPET and Tc-99m-MIBI gated SPET performed on the next day. The two standard deviation (2 SD) values for EDV, ESV and EF on the Bland-Altman plot were 29 mli, 19 mi and 12%, respectively, on repeated Tl-201 gated SPET, compared with 14 ml, 11 ml and 5.3% on repeated Tc-99m-MIBI gated SPET, The correlations were good (r=0.96, 0.97 and 0.87) between the two measurements of EDV, ESV and EF on repeated rest studies with Tl-201 and Tc-99m-MIBI gated SPET. However, Bland-Altman analysis revealed that the 2 SD values between the twomeasurements were 31 ml, 23 ml and 12%. We were able to score the wall motion in all cases using the 3D surface display of the QGS on Tl-201 gated SPET The kappa value of the wall motion grade on the repeated Tl-201 study was 0.35, while that of the wall motion grade on the repeated Tc-99m-MIBI study was 0.76, The kappa value was 0.49 for grading of wall motion on repeated rest studies with Tl-201 and Tc-99m-MIBI. In conclusion, QGS helped determine EDV, ESV, EF and wall motion on Tl-201 gated SPET, Because the EDV, ESV and EF were less reproducible on repeated Tl-201 gated SPET or on Tl-201 gated SPET and Tc-90m-MIBI gated SPET on the next day than on repeated Tc-99m-MIBI gated SPET, functional measurement on Tl-201 gated SPET did not seem to be interchangeable with that on Tc-99m-MIBI gated SPET.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 15:20:56