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Titolo:
A prospective study of fever and bacteremia after flexible fiberoptic bronchoscopy in children
Autore:
Picard, E; Schwartz, S; Goldberg, S; Glick, T; Villa, Y; Kerem, E;
Indirizzi:
Hebrew Univ Jerusalem, Sch Med, Shaare Zedek Med Ctr, Dept Pediat, IL-91031 Jerusalem, Israel Hebrew Univ Jerusalem Jerusalem Israel IL-91031 -91031 Jerusalem, Israel Tel Aviv Univ, Sch Math Sci, IL-69978 Tel Aviv, Israel Tel Aviv Univ Tel Aviv Israel IL-69978 th Sci, IL-69978 Tel Aviv, Israel
Titolo Testata:
CHEST
fascicolo: 2, volume: 117, anno: 2000,
pagine: 573 - 577
SICI:
0012-3692(200002)117:2<573:APSOFA>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
BRONCHOALVEOLAR LAVAGE; LUNG-DISEASE; COMPLICATIONS; ASPIRATION; CYTOKINES; PNEUMONIA;
Keywords:
adverse events; bacteremia; bronchoscopy; children; fever;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Kerem, E Hebrew Univ Jerusalem, Sch Med, Shaare Zedek Med Ctr, Dept Pediat, IL-91031 Jerusalem, Israel Hebrew Univ Jerusalem Jerusalem Israel IL-91031 rusalem, Israel
Citazione:
E. Picard et al., "A prospective study of fever and bacteremia after flexible fiberoptic bronchoscopy in children", CHEST, 117(2), 2000, pp. 573-577

Abstract

Study objectives: To assess the incidence of fever and bacteremia after fiberoptic bronchoscopy in immunocompetent children. Design: Prospective study. Patients: Immunocompetent children undergoing fiberoptic bronchoscopy between January 1997 and June 1998. Measurements and results: Ninety-one children were included in the study. Forty-four children (48%) developed fever within 24 h following bronchoscopy. Bacteremia was not detected in any of the cases at the time of the fever. Children who developed fever were younger than those who remained afebrile (mean age, 2.4 +/- 3.6 years vs 4.2 +/- 3.7 years; p = 0.025, In the fever group, 66% of the bronchoscopies were considered abnormal, compared to 45% in the nonfever group (p = 0.04). Of the fever group, 40.5% of BAL fluid cultures had significant bacterial growth, significantly higher compared tothe nonfever group (13.2%; p = 0.006). Of the 80 patients in whom BAL was performed, fever occurred in 52.9% compar ed to only 18.2% in those who didnot have BAL (p = 0.03). BAL fluid content of cell count, Lipid-laden macrophages, and interleukin-8 were not significantly different in both groups. In a logistic regression anal lsis, the significant predictors for developing fever were positive bacterial culture (relative risk, 5.1; 95% confidence interval, 1.6 to 16.4; p = 0.007) and abnormal bronchoscopic findings (relative risk, 3.1, 95% confidence interval, 1.2 to 8.3; p = 0.02). When age< 2 ears was included in the model, this factor became highly significant (relative risk, 5.01; 95% confidence interval, 1.83 to 13.75; p < 0.002). Conclusions: Fever following fiberoptic bronchoscopy is a common event in immunocompetent children and is not associated with bacteremia, Risks to develop this complication are age < 2)ears, positive bacterial cultures in BAL fluid, and abnormal bronchoscopic findings.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/06/20 alle ore 23:06:12