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Titolo:
Measurements of hindlimb blood flow recorded using Doppler ultrasound during administration of vasoactive agents in halothane-anesthetized horses
Autore:
Raisis, AL; Young, LE; Meire, HB; Taylor, PM; Blissitt, KJ; Marlin, D; Lekeux, P;
Indirizzi:
Ctr Equine Studies, Anim Hlth Trust, Newmarket CB8 7UU, Suffolk, England Ctr Equine Studies Newmarket Suffolk England CB8 7UU UU, Suffolk, England Univ London Kings Coll Hosp, Dept Radiol, London SE5 9RS, England Univ London Kings Coll Hosp London England SE5 9RS ndon SE5 9RS, England Univ Cambridge, Dept Clin Vet Med, Cambridge CB3 0ES, England Univ Cambridge Cambridge England CB3 0ES Med, Cambridge CB3 0ES, England Univ Edinburgh, Royal Dick Sch Vet Studies, Easterbush Vet Ctr, Dept Vet Clin Studies, Edinburgh EH25 9RG, Midlothian, Scotland Univ Edinburgh Edinburgh Midlothian Scotland EH25 9RG idlothian, Scotland
Titolo Testata:
VETERINARY RADIOLOGY & ULTRASOUND
fascicolo: 1, volume: 41, anno: 2000,
pagine: 64 - 72
SICI:
1058-8183(200001/02)41:1<64:MOHBFR>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
INPUT IMPEDANCE; WAVEFORMS;
Keywords:
equine; anesthesia; Doppler ultrasound; blood flow; waveform analysis; phenylephrine; sodium nitroprusside;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Raisis, AL Ctr Equine Studies, Anim Hlth Trust, Lanwades Pk, Newmarket CB87UU, Suffolk, England Ctr Equine Studies Lanwades Pk Newmarket Suffolk England CB8 7UU
Citazione:
A.L. Raisis et al., "Measurements of hindlimb blood flow recorded using Doppler ultrasound during administration of vasoactive agents in halothane-anesthetized horses", VET RAD ULT, 41(1), 2000, pp. 64-72

Abstract

The purpose of the study was to determine the ability of Doppler ultrasound to detect changes in femoral blood flow during pharmacologic manipulationof arterial blood pressure. Doppler ultrasonography was performed in the femoral vessels of six halothane-anesthetized horses before and during administration of phenylephrine HCl and sodium nitroprusside. The time-averaged mean velocity and volumetric flow were calculated. The contour of the velocity waveform was assessed, and the early diastolic deceleration slope (EDDS) and pulsatility index (PI) were calculated. Administration of phenylephrine HCl resulted in increased mean aortic blood pressure (MABP) by 40% (29.3-53.0%). This caused significant decrease in cardiac output (26.8 to 13.5 l/min), femoral arterial velocity (left artery 7.20 to 4.00 cm/s; right artery 5.01 to 3.39 cm/s) and volumetric flow (left artery 556 to 221 ml/min; right artery 397 to 193 ml/min) in the femoral vessels and significant increase in systemic vascular resistance (163 to 433 dyn-s/cm(5)), EDDS (la: 285to 468: ra: 250 to 481) and PI (la: 9.38 to 20.4; ra 17.1 to 29.1), Administration of sodium nitroprusside resulted in a decreased MABP of 27.2% (22.5-33%), This increased cardiac output (20.8 to 32.4 L/min), however, no significant changes were observed in femoral blood flow. Despite obvious changes in the waveform contour, no significant change occurred in EDDS or PI. These results suggest that Doppler ultrasound may be useful for measuring femoral blood flow in anesthetized horses. However, waveform analysis appearsto be limited when multiple changes occur in central and peripheral haemodynamics.

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Documento generato il 16/07/20 alle ore 05:20:29