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Titolo:
Past administration of beta-lactam antibiotics and increase in the emergence of beta-lactamase-producing bacteria in patients with orofacial odontogenic infections
Autore:
Kuriyama, T; Nakagawa, K; Karasawa, T; Saiki, Y; Yamamoto, E; Nakamura, S;
Indirizzi:
Kanazawa Univ, Sch Med, Dept Oral & Maxillofacial Surg, Kanazawa, Ishikawa9208640, Japan Kanazawa Univ Kanazawa Ishikawa Japan 9208640 awa, Ishikawa9208640, Japan Kanazawa Univ, Sch Med, Dept Bacteriol, Kanazawa, Ishikawa 9208640, Japan Kanazawa Univ Kanazawa Ishikawa Japan 9208640 wa, Ishikawa 9208640, Japan
Titolo Testata:
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS
fascicolo: 2, volume: 89, anno: 2000,
pagine: 186 - 192
SICI:
1079-2104(200002)89:2<186:PAOBAA>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
ANAEROBIC-BACTERIA; AMOXICILLIN-CLAVULANATE; TICARCILLIN-CLAVULANATE; BACTEROIDES-FRAGILIS; ANTIMICROBIAL AGENTS; ADULT PERIODONTITIS; PENICILLIN THERAPY; MICROBIOLOGY; RESISTANCE; SUSCEPTIBILITIES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
46
Recensione:
Indirizzi per estratti:
Indirizzo: Kuriyama, T Kanazawa Univ, Sch Med, Dept Oral & Maxillofacial Surg, Takara-machi 13-1,Kanazawa, Ishikawa 9208640, Japan Kanazawa Univ Takara-machi 13-1 Kanazawa Ishikawa Japan 9208640
Citazione:
T. Kuriyama et al., "Past administration of beta-lactam antibiotics and increase in the emergence of beta-lactamase-producing bacteria in patients with orofacial odontogenic infections", ORAL SURG O, 89(2), 2000, pp. 186-192

Abstract

Objective. The purpose of this study was to determine the current status of beta-lactamase-producing bacteria in orofacial odontogenic infections. Study design. Microbiologic data regarding purulent exudate from ill caseswith orofacial odontogenic infections were analyzed in relation to the past administration of beta-lactams. Results. beta-lactamase-producing bacteria were isolated more frequently from the beta-lactam-administered group (38.5%) than from the beta-lactam-nonadministered group (10.9%; P < .005), and they were isolated more frequently as the duration of administration increased. The predominant bacteria isolated included Prevotella (the most frequent isolate), viridans streptococci, Peptostreptococcus, and Fusobacterium, and 7.1% of total isolates produced beta-lactamase. Penicillin and cefazolin worked well with beta-lactamase-nonproducing Prevotella but were remarkably affected by beta-lactamase-producing Prevotella. Cefmetazole, sulbactam/cefoperazone, and imipenem worked well against both types of Prevotella,Conclusions. beta-lactams are still suitable for the first antimicrobial therapy in the treatment of these infections. However, because past beta-lactam administration increases the emergence of beta-lactamase-producing bacteria, beta-lactamase-stable antibiotics should be prescribed to patients with unresolved infections who have received beta-lactams.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 22:44:24