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Titolo:
Spatial distribution and characteristics of voltage-gated calcium signals within visual interneurons
Autore:
Haag, J; Borst, A;
Indirizzi:
Max Planck Soc, Friedrich Miescher Lab, D-72076 Tubingen, Germany Max Planck Soc Tubingen Germany D-72076 r Lab, D-72076 Tubingen, Germany
Titolo Testata:
JOURNAL OF NEUROPHYSIOLOGY
fascicolo: 2, volume: 83, anno: 2000,
pagine: 1039 - 1051
SICI:
0022-3077(200002)83:2<1039:SDACOV>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
INTRINSIC ELECTROPHYSIOLOGICAL CHARACTERISTICS; INTERCEREBRALIS NEUROSECRETORY-CELLS; ADULT LOCUSTA-MIGRATORIA; PLATE TANGENTIAL CELLS; FUNNEL-WEB SPIDER; CHANNEL CURRENTS; IONIC CURRENTS; CA2+ CURRENTS; MANDUCA-SEXTA; LOBULA PLATE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
53
Recensione:
Indirizzi per estratti:
Indirizzo: Borst, A Univ Calif Berkeley, ESPM, Div Insect Biol, 201 Wellmann Hall, Berkeley, CA 94720 USA Univ Calif Berkeley 201 Wellmann Hall Berkeley CA USA 94720 0 USA
Citazione:
J. Haag e A. Borst, "Spatial distribution and characteristics of voltage-gated calcium signals within visual interneurons", J NEUROPHYS, 83(2), 2000, pp. 1039-1051

Abstract

Spatial distribution and characteristics of voltage-gated calcium signals within visual interneurons. J. Neurophysiol. 83: 1039-1051, 2000. Most of our knowledge about insect calcium currents is derived from studies on cultured or dissociated somata. So far, only little data on calcium currents areavailable for: neurons including their dendritic and presynaptic structures. Here we combined the switched-electrode voltage-clamp technique with optical recording using calcium-sensitive dyes in identified fly visual interneurons in vivo to characterize the voltage dependence and dynamics of calcium currents quantitatively and in a spatially resolved way. For all three cell types considered, i.e., centrifugal horizontal (CH), horizontal system (HS), and vertical system (VS) cells, the activation curve is rather flat and covers a voltage range from -60 to -20 mV in dendritic as well as presynaptic areas of the cells. The calcium increase is fastest for CH cells witha time constant of similar to 70 ms. In HS and VS cells, the time constantamounts to 400-700 ms. The calcium dynamics as determined in different regions of the cells are similar except for a small segment between the axon and the dendrite in HS and VS cells, where the calcium increase is significantly faster. In summary, the results show the existence of a low-voltage-activated calcium current with little or no inactivation in dendritic as wellas presynaptic regions of fly lobula plate tangential cells.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/07/20 alle ore 13:30:21