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Titolo:
Pathogenic autoantibodies to neuronal proteins in neurological disorders
Autore:
Vincent, A; Lily, O; Palace, J;
Indirizzi:
John Radcliffe Hosp, Neurosci Grp, Inst Mol Med, Oxford OX3 9DS, England John Radcliffe Hosp Oxford England OX3 9DS Med, Oxford OX3 9DS, England Radcliffe Infirm, Dept Clin Neurol, Oxford OX1, England Radcliffe Infirm Oxford England OX1 ept Clin Neurol, Oxford OX1, England
Titolo Testata:
JOURNAL OF NEUROIMMUNOLOGY
fascicolo: 1-2, volume: 100, anno: 1999,
pagine: 169 - 180
SICI:
0165-5728(199912)100:1-2<169:PATNPI>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
EATON-MYASTHENIC-SYNDROME; GUILLAIN-BARRE-SYNDROME; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; ARTHROGRYPOSIS MULTIPLEX CONGENITA; GLUTAMIC-ACID DECARBOXYLASE; STIFF-MAN SYNDROME; ACETYLCHOLINE-RECEPTOR; ACQUIRED NEUROMYOTONIA; PLASMA-EXCHANGE; BASIC-PROTEIN;
Keywords:
autoantibodies; neuronal proteins; neurological disorders;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
72
Recensione:
Indirizzi per estratti:
Indirizzo: Vincent, A John Radcliffe Hosp, Neurosci Grp, Inst Mol Med, Oxford OX3 9DS, England John Radcliffe Hosp Oxford England OX3 9DS d OX3 9DS, England
Citazione:
A. Vincent et al., "Pathogenic autoantibodies to neuronal proteins in neurological disorders", J NEUROIMM, 100(1-2), 1999, pp. 169-180

Abstract

Autoantibodies to acetylcholine receptors and to voltage-gated calcium andpotassium channels are thought to be pathogenic in three peripheral neurological disorders: myasthenia gravis, the Lambert Eaten syndrome and acquired neuromyotonia. However, evidence for the role of antibodies in conditionsinvolving the central nervous system, is scanty or unclear. This review describes the ways in which the roles of autoantibodies have been defined in the peripheral diseases, and discusses the more controversial evidence for involvement of autoantibodies in some central disorders such as multiple sclerosis. (C) 1999 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 09:12:15