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Titolo:
Randomized controlled trials and consensus as a basis for interventions ininternal medicine
Autore:
Nordin-Johansson, A; Asplund, K;
Indirizzi:
Umea Univ Hosp, Dept Med, SE-90185 Umea, Sweden Umea Univ Hosp Umea Sweden SE-90185 osp, Dept Med, SE-90185 Umea, Sweden
Titolo Testata:
JOURNAL OF INTERNAL MEDICINE
fascicolo: 1, volume: 247, anno: 2000,
pagine: 94 - 104
SICI:
0954-6820(200001)247:1<94:RCTACA>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
ALCOHOL WITHDRAWAL SYMPTOMS; DOUBLE-BLIND; HEART-FAILURE; MYOCARDIAL-INFARCTION; ACTIVATED-CHARCOAL; ULCERATIVE-COLITIS; MULTIPLE-MYELOMA; DRUG-TREATMENT; GASTRIC-ULCER; METAANALYSIS;
Keywords:
evidence-based medicine; expert consensus; general internal medicine; interventions; randomized controlled trials;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
55
Recensione:
Indirizzi per estratti:
Indirizzo: Asplund, K Umea Univ Hosp, Dept Med, SE-90185 Umea, Sweden Umea Univ HospUmea Sweden SE-90185 ed, SE-90185 Umea, Sweden
Citazione:
A. Nordin-Johansson e K. Asplund, "Randomized controlled trials and consensus as a basis for interventions ininternal medicine", J INTERN M, 247(1), 2000, pp. 94-104

Abstract

Objectives. To estimate the proportion of routine clinical interventions in internal medicine that are supported by the results of randomized controlled trials or consensus amongst experienced internists. Design, Retrospective review of case records allowed one or more major diagnosis-intervention combination(s) to be identified for each patient. The scientific literature was searched for metaanalyses and randomized controlled trials in electronic databases that supported the specific intervention used. When support from randomized trials was lacking, possible consensus onmanagement was sought by asking national expert panels of experienced clinicians. Setting. Department of Medicine at a Swedish teaching hospital. Subjects, At total of 197 consecutively admitted medical inpatients. Results, Fifty per cent of the diagnosis-intervention combinations (186/369) were supported by results from randomized controlled trial evidence and 34% (125/369) were supported by consensus amongst experienced clinicians. The proportion of interventions based on randomised controlled trials was highest in patients with cardiac (64%) and other circulatory diagnoses (73%). There were no important differences between sexes or between age groups. Conclusions. Half of the interventions used in routine clinical practice amongst medical inpatients are supported by results from randomized controlled trials. These results refute popular claims that only a small proportionof medical interventions are supported by scientific evidence.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 20:22:30