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Titolo:
Ethanol, memory, and hippocampal function: A review of recent findings
Autore:
White, AM; Matthews, DB; Best, PJ;
Indirizzi:
Miami Univ, Dept Psychol, Oxford, OH 45056 USA Miami Univ Oxford OH USA 45056 i Univ, Dept Psychol, Oxford, OH 45056 USA Miami Univ, Ctr Neurosci, Oxford, OH 45056 USA Miami Univ Oxford OH USA 45056 i Univ, Ctr Neurosci, Oxford, OH 45056 USA Univ N Carolina, Skipper Bowles Ctr Alcohol Studies, Chapel Hill, NC USA Univ N Carolina Chapel Hill NC USA Alcohol Studies, Chapel Hill, NC USA
Titolo Testata:
HIPPOCAMPUS
fascicolo: 1, volume: 10, anno: 2000,
pagine: 88 - 93
SICI:
1050-9631(2000)10:1<88:EMAHFA>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
LONG-TERM POTENTIATION; MEDIAL SEPTAL AREA; SPATIAL WORKING-MEMORY; EVOKED ELECTROPHYSIOLOGICAL ACTIVITY; VENTRAL TEGMENTAL AREA; FIMBRIA-FORNIX LESIONS; CA1 PYRAMIDAL NEURONS; GATED ION CHANNELS; PROTEIN-KINASE-C; THETA-RHYTHM;
Keywords:
hippocampus; learning; GABA; NMDA; plasticity;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
109
Recensione:
Indirizzi per estratti:
Indirizzo: White, AM VA Med Ctr, Bldg 16,Rm 24, Durham, NC 27705 USA VA Med Ctr Bldg 16,Rm 24 Durham NC USA 27705 urham, NC 27705 USA
Citazione:
A.M. White et al., "Ethanol, memory, and hippocampal function: A review of recent findings", HIPPOCAMPUS, 10(1), 2000, pp. 88-93

Abstract

For well over a century, ethanol was believed to exert its effects on cognition and behavior by producing a ubiquitous depression of central nervous system activity. A general disruption in brain function was consistent withthe belief that ethanol's effects on cognition and behavior were also quite general. Substantial evidence now indicates that ethanol produces a host of selective effects on neural activity, resulting in regional differences in ethanol's effects in the brain. Consistent with such evidence, recent research suggests that ethanol's effects on cognition and behavior are not asglobal as previously assumed. The present paper discusses evidence that many of ethanol's effects on learning and memory stem from altered cellular activity in the hippocampus and related structures. Potential mechanisms forethanol's disruption of hippocampal function are reviewed. Evidence suggests that ethanol disrupts activity in the hippocampus by interacting directly with hippocampal neurons and by interacting with critical hippocampal afferents. Hippocampus 2000; 10:88-93. (C) 2000 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 07:32:34