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Titolo:
Clinical, histological and immunopathological features of 58 patients withsubacute cutaneous lupus erythematosus - A review by the Italian Group of Immunodermatology
Autore:
Parodi, A; Caproni, M; Cardinali, C; Bernacchi, E; Fuligni, A; De Panfilis, G; Zane, C; Papini, M; Veller, FC; Vaccaro, M; Fabbri, P;
Indirizzi:
Univ Florence, Dermatol Clin 2, I-50121 Florence, Italy Univ Florence Florence Italy I-50121 tol Clin 2, I-50121 Florence, Italy Univ Genoa, Sez Dermatol, DISEM, Genoa, Italy Univ Genoa Genoa ItalyUniv Genoa, Sez Dermatol, DISEM, Genoa, Italy Spedali Civili, Div Dermatol, I-25125 Brescia, Italy Spedali Civili Brescia Italy I-25125 iv Dermatol, I-25125 Brescia, Italy Univ Perugia, Sez Dermatol Terni, I-06100 Perugia, Italy Univ Perugia Perugia Italy I-06100 ermatol Terni, I-06100 Perugia, Italy Univ Padua, Dermatol Clin, I-35100 Padua, Italy Univ Padua Padua Italy I-35100 adua, Dermatol Clin, I-35100 Padua, Italy Univ Messina, Dermatol Clin, I-98100 Messina, Italy Univ Messina MessinaItaly I-98100 Dermatol Clin, I-98100 Messina, Italy
Titolo Testata:
DERMATOLOGY
fascicolo: 1, volume: 200, anno: 2000,
pagine: 6 - 10
SICI:
1018-8665(2000)200:1<6:CHAIFO>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
SS-A ANTIBODY; SJOGRENS SYNDROME; NEONATAL LUPUS; DISEASE; CRITERIA; RO; HYDROCHLOROTHIAZIDE; CLASSIFICATION; PARTICLES; PATTERN;
Keywords:
lupus erythematosus, subacute cutaneous; psoriasiform lesions; annular lesions;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
39
Recensione:
Indirizzi per estratti:
Indirizzo: Fabbri, P Univ Florence, Dermatol Clin 2, Via Pergola 58, I-50121 Florence, Italy Univ Florence Via Pergola 58 Florence Italy I-50121 ence, Italy
Citazione:
A. Parodi et al., "Clinical, histological and immunopathological features of 58 patients withsubacute cutaneous lupus erythematosus - A review by the Italian Group of Immunodermatology", DERMATOLOGY, 200(1), 2000, pp. 6-10

Abstract

Background: Subacute cutaneous lupus erythematosus (SCLE) is a distinct subset of cutaneous lupus erythematosus clinically characterized by psoriasiform and/or annular lesions and by a mild or absent systemic involvement. Objective: The Italian Group of Immunodermatology of the Italian Society of Dermatology and Venereology reviewed the cases of SCLE seen in 10 years (1987-1996). Patients: Forty-six women and 12 men have been retrospectively studied, 42% had annular lesions, 39% psoriasiform ones and 16% both. Results:Lesions were mainly localized on the neck and face and relapsed in spring and autumn. Seventeen patients had 4 or more American College of Rheumatology criteria and could be classified as having systemic lupus erythematosus. The most frequent histopathological alterations were epidermal atrophy, hydropic degeneration of the basal layer and perivascular lymphocytic infiltrate. Deposits of immunoglobulins and C3 at the dermo-epidermal junction on the clinically involved skin were present in 86% of the patients. Dust-likeparticles in the epidermis were only found in 3% of cases. Anti-Ro/SSA antibodies were found in 71% of the cases and anti-dsDNA only in 5% of cases. Conclusions: SCLE is a particular subset of cutaneous lupus erythematosus with peculiar clinical and immunopathological features. Copyright (R) 2000 S. Karger AG, Basel.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 23:58:16