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Titolo:
Vascular cell adhesion molecule-1 in normal, failed, and ectopic pregnancy
Autore:
Yair, D; Geva, E; Eshed-Englender, T; Gamzu, R; Lessing, JB; Bar-Am, A; Amit, A;
Indirizzi:
Tel Aviv Univ, Dept Obstet & Gynecol, Tel Aviv Sourasky Med Ctr, Sackler Fac Med,Lis Matern Hosp, IL-64239 Tel Aviv, Israel Tel Aviv Univ Tel Aviv Israel IL-64239 n Hosp, IL-64239 Tel Aviv, Israel Tel Aviv Univ, Sara Racine In Vitro Fertilizat Unit, Tel Aviv Sourasky MedCtr, Sackler Fac Med,Lis Matern Hosp, IL-64239 Tel Aviv, Israel Tel Aviv Univ Tel Aviv Israel IL-64239 n Hosp, IL-64239 Tel Aviv, Israel Tel Aviv Univ, Sackler Fac Med, Tel Aviv Sourasky Med Ctr, Dept Oncol,Cytokine Res Lab, IL-69978 Tel Aviv, Israel Tel Aviv Univ Tel Aviv Israel IL-69978 es Lab, IL-69978 Tel Aviv, Israel
Titolo Testata:
AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
fascicolo: 2, volume: 43, anno: 2000,
pagine: 92 - 97
SICI:
1046-7408(200002)43:2<92:VCAMIN>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
SINGLE SERUM PROGESTERONE; E-SELECTIN; CYTOTROPHOBLASTS; PREECLAMPSIA; EXPRESSION; ANGIOGENESIS; ACCURACY; ICAM-1; VCAM-1;
Keywords:
cell adhesion molecules; implantation; placentation; progesterone; beta HCG; soluble VCAM-1;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Yair, D Tel Aviv Univ, Dept Obstet & Gynecol, Tel Aviv Sourasky Med Ctr, Sackler Fac Med,Lis Matern Hosp, 6 Weizmann St, IL-64239 Tel Aviv, Israel Tel Aviv Univ 6 Weizmann St Tel Aviv Israel IL-64239 Aviv, Israel
Citazione:
D. Yair et al., "Vascular cell adhesion molecule-1 in normal, failed, and ectopic pregnancy", AM J REPROD, 43(2), 2000, pp. 92-97

Abstract

PROBLEM: Vascular cell adhesion molecule-1 (VCAM-1) is involved in early pregnancy establishment. This study sought to determine whether soluble VCAM-1 (sVCAM-1) serum levels differ among normal, failed, and ectopic pregnancy, its capacity to serve as a marker for pregnancy viability or ectopic pregnancy, and its correlation with serum progesterone and beta human chorionic gonadotrophin (beta HCG) levels. METHOD OF STUDY: Maternal serum samples were obtained from 20 women with ectopic, 10 with normal, and 10 with failed intra-uterine pregnancy, all of comparable gestational age. Samples were assayed for sVCAM-1, progesterone,and beta HCG by specific assays. RESULTS: The median serum level of sVCAM-1 was comparable between the three pregnancy types (normal: 578.3 ng/mL, range 434.4-699.5 ng/mL; failed: 567.8 ng/mL, range 401.9-669.5 ng/mL; and ectopic: 470.7 ng/mL range, 328.2-1151.1 ng/mL). Serum levels sVCAM-1 were not significantly correlated with beta HCG or progesterone levels. CONCLUSION: sVCAM-1 is not appropriate to serve as a marker for pregnancy viability or ectopic pregnancy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/08/20 alle ore 07:08:32