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Titolo:
Preoperative B-mode ultrasound plaque appearance compared with carotid endarterectomy specimen histology
Autore:
Schulte-Altedorneburg, G; Droste, DW; Haas, N; Kemeny, V; Nabavi, DG; Fuzesi, L; Ringelstein, EB;
Indirizzi:
Univ Munster, Dept Neurol, D-4400 Munster, Germany Univ Munster Munster Germany D-4400 Dept Neurol, D-4400 Munster, Germany Univ Aachen, Dept Pathol, Aachen, Germany Univ Aachen Aachen GermanyUniv Aachen, Dept Pathol, Aachen, Germany
Titolo Testata:
ACTA NEUROLOGICA SCANDINAVICA
fascicolo: 3, volume: 101, anno: 2000,
pagine: 188 - 194
SICI:
0001-6314(200003)101:3<188:PBUPAC>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
THERAPEUTIC IMPLICATIONS; CEREBRAL SYMPTOMS; HEMORRHAGE; MORPHOLOGY; DISEASE;
Keywords:
ultrasonics; carotid endarterectomy; histology; carotid artery diseases;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Schulte-Altedorneburg, G Zentralklin Augsburg, Dept Radiol, Stenglinstr 2,D-86156 Augsburg, Germany Zentralklin Augsburg Stenglinstr 2 Augsburg Germany D-86156
Citazione:
G. Schulte-Altedorneburg et al., "Preoperative B-mode ultrasound plaque appearance compared with carotid endarterectomy specimen histology", ACT NEUR SC, 101(3), 2000, pp. 188-194

Abstract

In carotid artery stenosis both the degree of the lesion and its plaque morphology are thought to be associated with the carrier's thromboembolic risk. In this study we evaluated the diagnostic preciseness of non-invasively B-mode ultrasound in predicting the histopathological plaque structure. We examined 44 patients with > 50% ICA stenosis by B-mode within 6 weeks priorto carotid endarterectomy. At the affected bifurcations, up to 10 different regions of interest (ROI) per artery were investigated. Plaque appearancewas classified according to 6 subtypes considering different ultrasonic plaque features. Postoperatively, plaque specimens were examined histopathologicaIly for their relative content of calcification, fibrous tissue and different soft tissue. B-mode ultrasound was compared with histopathological features in ROI. A total of 265 regions of interest were evaluated. In mainly echolucent types of plaques, atheromatous debris was most frequently seen, whereas fibrosis was rare. Homogeneous echolucent plaques showed a high proportion of cholesterol and/or recent haemorrhage. Thrombosis at the plaque surface was often seen in "completely echolucent" plaque type (each P < 0.001). Carotid B-mode ultrasonography is able to predict the histopathological components and the texture of carotid plaques.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/21 alle ore 08:32:02