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Titolo:
Oxidative stress and age-related cataract
Autore:
Ottonello, S; Foroni, C; Carta, A; Petrucco, S; Maraini, G;
Indirizzi:
Univ Parma, Inst Ophthalmol, Fac Med, I-43100 Parma, Italy Univ Parma Parma Italy I-43100 Ophthalmol, Fac Med, I-43100 Parma, Italy Univ Parma, Fac Sci, Ist Sci Biochim, I-43100 Parma, Italy Univ Parma Parma Italy I-43100 ci, Ist Sci Biochim, I-43100 Parma, Italy
Titolo Testata:
OPHTHALMOLOGICA
fascicolo: 1, volume: 214, anno: 2000,
pagine: 78 - 85
SICI:
0030-3755(200001/02)214:1<78:OSAAC>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSTERIOR SUBCAPSULAR CATARACTS; IRON REGULATORY PROTEIN-1; IRREVERSIBLE LENS DAMAGE; RESPONSIVE ELEMENT; HYDROGEN-PEROXIDE; SUNLIGHT EXPOSURE; EPITHELIAL-CELLS; C-JUN; RISK; METALLOTHIONEIN;
Keywords:
cataract; oxidative stress; lens;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
48
Recensione:
Indirizzi per estratti:
Indirizzo: Maraini, G Univ Parma, Inst Ophthalmol, Fac Med, Via Gramsci 14, I-43100 Parma, Italy Univ Parma Via Gramsci 14 Parma Italy I-43100 100 Parma, Italy
Citazione:
S. Ottonello et al., "Oxidative stress and age-related cataract", OPHTHALMOLA, 214(1), 2000, pp. 78-85

Abstract

The authors review the available evidence supporting the possible role of oxidative stress in cataract formation from an epidemiological and a clinical point of view. They discuss in more detail what is presently known aboutthe molecular mechanisms of response of the mammalian lens to an oxidativeinsult and report unpublished data on gene modulation upon oxidative stress in a bovine lens model. Main research endeavors that seem to be a most promising source of new insights into the problem of age-related cataract formation are briefly discussed. Copyright (C) 2000 S. Karger AG, Basel.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/09/20 alle ore 20:16:03