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Titolo:
Adenosine with cold blood cardioplegia during coronary revascularization
Autore:
Rinne, T; Laurikka, J; Penttila, I; Kaukinen, S;
Indirizzi:
Tampere Univ Hosp, Dept Anesthesia & Intens Care, FIN-33521 Tampere, Finland Tampere Univ Hosp Tampere Finland FIN-33521 , FIN-33521 Tampere, Finland Tampere Univ Hosp, Dept Surg, FIN-33521 Tampere, Finland Tampere Univ Hosp Tampere Finland FIN-33521 , FIN-33521 Tampere, Finland Univ Tampere, Sch Med, FIN-33101 Tampere, Finland Univ Tampere Tampere Finland FIN-33101 h Med, FIN-33101 Tampere, Finland Kuopio Univ Hosp, Dept Clin Chem, SF-70210 Kuopio, Finland Kuopio Univ Hosp Kuopio Finland SF-70210 Chem, SF-70210 Kuopio, Finland
Titolo Testata:
JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA
fascicolo: 1, volume: 14, anno: 2000,
pagine: 18 - 20
SICI:
1053-0770(200002)14:1<18:AWCBCD>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
POTASSIUM CARDIOPLEGIA; CELLS; CARDIOMYOCYTES; HEART;
Keywords:
adenosine; blood cardioplegia; cardioprotection; aortocoronary bypass; troponin-T; troponin-I;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Rinne, T Tampere Univ Hosp, Dept Anesthesia & Intens Care, POB 2000, FIN-33521 Tampere, Finland Tampere Univ Hosp POB 2000 Tampere Finland FIN-33521re, Finland
Citazione:
T. Rinne et al., "Adenosine with cold blood cardioplegia during coronary revascularization", J CARDIOTHO, 14(1), 2000, pp. 18-20

Abstract

Objective: To investigate whether adenosine in association with blood cardioplegia results in more rapid cardiac arrest or improved myocardial protection. Design: A prospective, randomized, placebo-controlled double-blind clinical study,Setting: Operative and intensive care units in a university hospital, Finland. Participants: Forty patients undergoing primary, elective coronary revascularization. Intervention: Adenosine as a bolus dose, 12 mg intravenously, was given immediately before the induction of blood cardioplegia. Measurements and Main Results: There were nonsignificantly higher serial serum values of CK (MB) (p = 0.33), troponin-T (p = 0.23), and troponin-I (p= 0.10) in the adenosine group, There were no differences between the groups in arrest time, blood pressure decrease, or lactate extraction. Conclusions: The adenosine regimen used in this study did not cause more rapid arrest with blood cardioplegia, The effect on cardioprotection was insignificant. Copyright (C) 2000 by W.B. Saunders Company.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/07/20 alle ore 21:50:18