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Titolo:
Differential expression of cadherin adhesion receptors in neural retina ofthe postnatal mouse
Autore:
Honjo, M; Tanihara, H; Suzuki, S; Tanaka, T; Honda, Y; Takeichi, M;
Indirizzi:
Kyoto Univ, Grad Sch Biostudies, Dept Cell & Dev Biol, Sakyo Ku, Kyoto 6068502, Japan Kyoto Univ Kyoto Japan 6068502 Dev Biol, Sakyo Ku, Kyoto 6068502, Japan Kyoto Univ, Grad Sch Med, Dept Ophthalmol & Visual Sci, Sakyo Ku, Kyoto, Japan Kyoto Univ Kyoto Japan Ophthalmol & Visual Sci, Sakyo Ku, Kyoto, Japan
Titolo Testata:
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
fascicolo: 2, volume: 41, anno: 2000,
pagine: 546 - 551
SICI:
0146-0404(200002)41:2<546:DEOCAR>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
CLASSIC CADHERINS; AMACRINE CELLS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
12
Recensione:
Indirizzi per estratti:
Indirizzo: Takeichi, M Kyoto Univ, Grad Sch Biostudies, Dept Cell & Dev Biol, Sakyo Ku, Kyoto 6068502, Japan Kyoto Univ Kyoto Japan 6068502 akyo Ku, Kyoto 6068502, Japan
Citazione:
M. Honjo et al., "Differential expression of cadherin adhesion receptors in neural retina ofthe postnatal mouse", INV OPHTH V, 41(2), 2000, pp. 546-551

Abstract

PURPOSE. To determine the expression pattern of multiple subtypes of cadherin adhesion receptor in postnatal mouse neural retina. METHODS. The expression of N-cadherin, R-cadherin, cadherin-6, cadherin-8,and cadherin-ll in retinas at postnatal days 0 to 42 was analyzed by in situ hybridization of mRNA as well as by immunohistochemistry. RESULTS. Each cadherin was expressed by different cell populations of the retina, and the following expression patterns were established by postnatalday 14: in the ganglion cell layer, all these molecules were expressed, but each occurred only in a subset of the cells. Likewise, in the inner nuclear layer, R-cadherin and cadherin-6 and -8 were expressed by a. restricted population of amacrine cells, and cadherin-8 also by a subpopulation of bipolar cells. All horizontal cells expressed R-cadherin. and Muller cells expressed N-cadherin and cadherin-11. Proteins of R-cadherin and cadherin-6 were concentrated in neuropil layers. CONCLUSIONS. The pattern of differential expression of the five cadherins supports the idea that these molecules may play a role in selective cell interactions within the heterogeneous cell pool of the neural retina.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/09/20 alle ore 09:17:44