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Titolo:
Computerized reminders to monitor liver function to improve the use of etretinate
Autore:
Koide, D; Ohe, K; Ross-Degnan, D; Kaihara, S;
Indirizzi:
Univ Tokyo, Fac Med, Dept Pharmacoepidemiol, Bunkyo Ku, Tokyo 1138655, Japan Univ Tokyo Tokyo Japan 1138655 pidemiol, Bunkyo Ku, Tokyo 1138655, Japan Tokyo Univ Hosp, Hosp Comp Ctr, Bunkyo Ku, Tokyo 1138655, Japan Tokyo UnivHosp Tokyo Japan 1138655 Ctr, Bunkyo Ku, Tokyo 1138655, Japan Dept Ambulatory Care & Prevent, Boston, MA 02215 USA Dept Ambulatory Care & Prevent Boston MA USA 02215 , Boston, MA 02215 USA Natl Okura Hosp, Setagaya Ku, Tokyo 1570074, Japan Natl Okura Hosp TokyoJapan 1570074 p, Setagaya Ku, Tokyo 1570074, Japan
Titolo Testata:
INTERNATIONAL JOURNAL OF MEDICAL INFORMATICS
fascicolo: 1, volume: 57, anno: 2000,
pagine: 11 - 19
SICI:
1386-5056(200001)57:1<11:CRTMLF>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
ADVERSE DRUG EVENTS; MEDICAL RECORD SYSTEM; HOSPITALIZED-PATIENTS; CONTROLLED TRIAL; PREVENTIVE CARE; CLINICAL-TRIAL; THERAPY; ERRORS; PHYSICIANS; COSTS;
Keywords:
quality of care; drug utilization; hospital computer system; intervention; computerized alert;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
58
Recensione:
Indirizzi per estratti:
Indirizzo: Koide, D Univ Tokyo, Fac Med, Dept Pharmacoepidemiol, Bunkyo Ku, 7-3-1 Hongou, Tokyo 1138655, Japan Univ Tokyo 7-3-1 Hongou Tokyo Japan 1138655 Tokyo 1138655, Japan
Citazione:
D. Koide et al., "Computerized reminders to monitor liver function to improve the use of etretinate", INT J MED I, 57(1), 2000, pp. 11-19

Abstract

Objective: to determine whether computerized reminders during the process of prescribing can improve the use of drugs requiring prior laboratory testing according to the indications listed in the Drug Package Insert. Measures: Change in proportion of appropriate prescribing and frequency of severe hepatotoxicity between pre- and post-intervention. Methods: etretinate, a medication indicated for psoriasis, was selected as a monitored drug becauseit was the most prescribed of all the identified drugs that require specific prior laboratory tests. Computerized reminders are designed to alert a physician who is about to prescribe etretinate either without the alanine aminotranceferase (ALT) test or the aspartate aminotransferase (AST) test within 3 months or despite abnormality in ALT or AST. Data on alerts were gathered by using electronic mail whenever alerts occurred. Results: prescriptions of etretinate with normal ALT or AST results within the previous three months increased suddenly from 25.9% (127/491) in the pre-intervention period to 66.2% (353/533) in the post-intervention period (P < 0.0001). Moreover, three patients who used etretinate had markedly abnormal tests in the pre-intervention period, but none of the patients were classified in this wayin the post-intervention period. Conclusions: the computerized reminders appear to improve physicians' use of a drug requiring specific prior laboratory tests. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 13/07/20 alle ore 18:09:08