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Titolo:
Spinal cord magnetic resonance imaging in suspected multiple sclerosis
Autore:
Nijeholt, GJLA; Uitdehaag, BMJ; Bergers, E; Castelijns, JA; Polman, CH; Barkhof, F;
Indirizzi:
Free Univ Amsterdam Hosp, Dept Radiol, Dutch MS MRI Ctr, NL-1081 HV Amsterdam, Netherlands Free Univ Amsterdam Hosp Amsterdam Netherlands NL-1081 HV m, Netherlands Free Univ Amsterdam Hosp, Dept Neurol, Dutch MS MRI Ctr, NL-1081 HV Amsterdam, Netherlands Free Univ Amsterdam Hosp Amsterdam Netherlands NL-1081 HV m, Netherlands
Titolo Testata:
EUROPEAN RADIOLOGY
fascicolo: 2, volume: 10, anno: 2000,
pagine: 368 - 376
SICI:
0938-7994(2000)10:2<368:SCMRII>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
MULTIARRAY COILS; MRI; CRITERIA; BRAIN; ABNORMALITIES; PARAMETERS; ECHO;
Keywords:
multiple sclerosis; magnetic resonance imaging; spinal imaging; diagnosis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
16
Recensione:
Indirizzi per estratti:
Indirizzo: Nijeholt, GJLA Free Univ Amsterdam Hosp, Dept Radiol, Dutch MS MRI Ctr, DeBoelelaan 117,NL-1081 HV Amsterdam, Netherlands Free Univ Amsterdam Hosp De Boelelaan 117 Amsterdam Netherlands NL-1081 HV
Citazione:
G.J.L.A. Nijeholt et al., "Spinal cord magnetic resonance imaging in suspected multiple sclerosis", EUR RADIOL, 10(2), 2000, pp. 368-376

Abstract

We examined the value of spinal cord magnetic resonance imaging (MRI) in the diagnostic work-up of multiple sclerosis (MS). Forty patients suspected of having MS were examined within nibs after the start of symptoms. Disability assessed, and symptoms were categorized as either brain or spinal cord. Work-up further included fluid analysis and standard proton-density, T2-, and T1-weighted gadolinium-enhanced brain and spinal cord MRL. Patients were categorized as either clinically definite MS (II = 13), laboratory-supported definite MS (II = 14), or clinically probable MS (n = 4); four patientshad clinically probable MS, and in nine MS was suspected. Spinal cord abnormalities were found in 35 of 40 patients (87.5 %), consisting of focal lesions in 31, only diffuse abnormalities in two,and both in two. Asymptomaticspinal cord lesions occurred in six patients. All patients with diffuse spinal cord abnormality had clear spinal cord. symptoms and a primary progressive disease course. In clinically definite MS, the inclusion of spinal imaging increased the sensitivity of MRI to 100 %. Seven patients without a definite diagnosis had clinically isolated syndromes involving the spinal cord. Brain MRI was inconclusive, while all had focal spinal cord lesions which explained symptoms and ruled out other causes. Two other patients had atypical brain abnormalities suggesting ischemic/vascular disease. No spinal cord abnormalities were found, and during follow-up MS was ruled out. Spinalcord abnormalities are common in suspected MS, and may occur asymptomatic. Although diagnostic classification is seldom, spinal cord imaging increases diagnostic sensitivity of MRI in patients with suspected MS. In addition,patients with primary progressive MS may atypical lesions may be improved.ly be earlier diagnosed. Finally, differentiation with atypical lesions may be improved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 14/08/20 alle ore 16:59:07