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Titolo:
Serum troponins T and I after elective cardioversion
Autore:
Lund, M; French, JK; Johnson, RN; Williams, BF; White, HD;
Indirizzi:
Green Lane Hosp, Dept Cardiol, Cardiovasc Res Unit, Auckland 1030, New Zealand Green Lane Hosp Auckland New Zealand 1030 it, Auckland 1030, New Zealand Green Lane Hosp, Dept Clin Biochem, Auckland 3, New Zealand Green Lane Hosp Auckland New Zealand 3 Biochem, Auckland 3, New Zealand
Titolo Testata:
EUROPEAN HEART JOURNAL
fascicolo: 3, volume: 21, anno: 2000,
pagine: 245 - 253
SICI:
0195-668X(200002)21:3<245:STTAIA>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE MYOCARDIAL-INFARCTION; ACUTE CORONARY SYNDROMES; ELECTRICAL CARDIOVERSION; RISK STRATIFICATION; CARDIAC TROPONINS; ENZYME-RELEASE; COUNTERSHOCK; FIBRILLATION; VALIDATION; INCREASE;
Keywords:
cardioversion; CKMB (mass); myocardial proteins; troponin I; troponin T;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
36
Recensione:
Indirizzi per estratti:
Indirizzo: White, HD Green Lane Hosp, Dept Cardiol, Cardiovasc Res Unit, Private Bag 92 189, Auckland 1030, New Zealand Green Lane Hosp Private Bag 92 189 Auckland New Zealand 1030 nd
Citazione:
M. Lund et al., "Serum troponins T and I after elective cardioversion", EUR HEART J, 21(3), 2000, pp. 245-253

Abstract

Aims To describe the pattern of release of five myocardial proteins after elective cardioversion. Methods and Results We measured serum levels of the myocardial proteins creatine kinase, creatine kinase MB mass, myoglobin, troponin T and troponin I serially from baseline to 24 h after 72 elective cardioversion attempts. The total energy used for attempted cardioversion was 408 +/- 318 J (range 50 to 1280 J), Maximal creatine kinase levels (median 232 IU . l(-1), interquartile range 91 to 1152 IU. l(-1)) occurred at 24 h and correlated with the total energy delivered (r=0.75, P<0.0001). The peak creatine kinase MB mass levels exceeded the discrimination level for myocardial injury(greater than or equal to 5 mu g . l(-1)) in seven patients (10%). The peak myoglobin levels were elevated (greater than or equal to 85 mu g. l(-1))in 40 patients (56%) and correlated with the peak creatine kinase levels (r=0.83, P<0.0001). Troponin T reached the discrimination level (0.10 mu g . l(-1)) in one patient with a serum creatinine level of 0.16 mmol. l(-1) and severe left ventricular impairment, Twelve patients had baseline troponin I levels above our prespecified discrimination level of 0.4 mu g . l(-1) (range 0.4 to3.1 mu g . l(-1)), which did not increase after cardioversion. In two patients the levels rose from <0.4 mu g . l(-1) to 0.5 mu g . l(-1) and 0.6 mu g . l(-1) respectively. Conclusions Troponin T levels do not rise after elective cardioversion. The minor increases in troponin I may reflect our choice of discrimination level. Cardiac troponins are useful in determining whether arrhythmias requiring emergency cardioversion are primary or secondary to myocardial infarction. (C) 2000 The European Society of Cardiology.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 13/07/20 alle ore 10:19:56