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Titolo:
Application of human complement factor H-related protein (BTA TRAK) in monitoring patients with bladder cancer
Autore:
Malkowicz, SB;
Indirizzi:
Univ Penn, Med Ctr, Div Urol, Philadelphia, PA 19104 USA Univ Penn Philadelphia PA USA 19104 Div Urol, Philadelphia, PA 19104 USA
Titolo Testata:
UROLOGIC CLINICS OF NORTH AMERICA
fascicolo: 1, volume: 27, anno: 2000,
pagine: 63 -
SICI:
0094-0143(200002)27:1<63:AOHCFH>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
VOIDED URINE CYTOLOGY; PROSTATE-CANCER; TUMOR ANTIGEN; WASH CYTOLOGY; MARKER; SENSITIVITY; SPECIFICITY; DIAGNOSIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
40
Recensione:
Indirizzi per estratti:
Indirizzo: Malkowicz, SB Univ Penn, Med Ctr, Div Urol, 1 Rhoads Pavillion,3400 SpruceSt, Philadelphia, PA 19104 USA Univ Penn 1 Rhoads Pavillion,3400 Spruce StPhiladelphia PA USA 19104
Citazione:
S.B. Malkowicz, "Application of human complement factor H-related protein (BTA TRAK) in monitoring patients with bladder cancer", UROL CLIN N, 27(1), 2000, pp. 63

Abstract

The BTA TRAK assay is a quantitative sandwich format enzyme immunoassay performed in a reference laboratory. It measures levels of human complement factor H-related protein (hCFHrp) which is similar to human complement factor H. Test characteristics reveal an overall sensitivity of 68% to 77.5% anda specificity of 50%-75%. Retrospective analysis of urine specimens employing hazard analysis suggests that BTA TRAK may have a role as a quantitative diagnostic marker in monitoring bladder cancer patients. Prospective studies are required to validate this application and other uses of the BTA TRAK assay in the management of bladder cancer patients.

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Documento generato il 29/11/20 alle ore 16:13:02