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Titolo:
Effects of advanced aging on plasma catecholamine responses to the cold pressor test
Autore:
Pascualy, M; Petrie, EC; Brodkin, K; Peskind, ER; Veith, RC; Raskind, MA;
Indirizzi:
MIRECC, NW Network, Seattle, WA USA MIRECC Seattle WA USAMIRECC, NW Network, Seattle, WA USA Univ Washington, Dept Psychiat & Behav Sci, Seattle, WA 98195 USA Univ Washington Seattle WA USA 98195 t & Behav Sci, Seattle, WA 98195 USA Vet Adm Med Ctr, Ctr Geriatr Res Educ & Clin, Seattle, WA 98108 USA Vet Adm Med Ctr Seattle WA USA 98108 s Educ & Clin, Seattle, WA 98108 USA
Titolo Testata:
NEUROBIOLOGY OF AGING
fascicolo: 6, volume: 20, anno: 1999,
pagine: 637 - 642
SICI:
0197-4580(199911/12)20:6<637:EOAAOP>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
SYMPATHETIC NERVOUS-SYSTEM; NOREPINEPHRINE KINETICS; BLOOD-PRESSURE; MYOCARDIAL-INFARCTION; AGE-DIFFERENCES; HEALTHY HUMANS; DEPRESSION; INCREASE; STRESS; MUSCLE;
Keywords:
aging; norepinephrine; epinephrine; cold pressor test; sympathetic nervous system;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
37
Recensione:
Indirizzi per estratti:
Indirizzo: Pascualy, M MIRECC, NW Network, Seattle, WA USA MIRECC Seattle WA USAMIRECC, NW Network, Seattle, WA USA
Citazione:
M. Pascualy et al., "Effects of advanced aging on plasma catecholamine responses to the cold pressor test", NEUROBIOL A, 20(6), 1999, pp. 637-642

Abstract

Increased basal norepinephrine (NE) concentrations have been demonstrated repeatedly in human aging, but these studies have included almost exclusively "early aging" subjects younger than age 75. We asked if "advanced aging"(over age 80) enhanced the effects of early aging on plasma NE and epinephrine (EPI) concentrations at rest and in response to the cold presser test (CPT). Eight medically well, cognitively intact advanced aging subjects (84.4 +/- 0.9 years); 28 medically well cognitively intact early aging subjects (70.3 +/- 1.3 years), and 19 medically well young subjects (25.4 +/- 0.9 years) were studied. Both basal NE and the acute NE increase after CPT weresignificantly higher in advanced aging than in either early aging or youngsubjects. Plasma EPI concentrations were higher in the advanced aging group in the other groups and an acute plasma EPT increase after CPT occurred only in the advanced aging group. These results suggest specific effects of advanced aging on both the sympathoneural and sympathoadrenomedullary components of the sympathetic nervous system. (C) 2000 Elsevier Science Inc. Allrights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 11:15:11