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Titolo:
Abnormal visual event-related potentials in obsessive-compulsive disorder without panic disorder or depression comorbidity
Autore:
Di Russo, F; Zaccara, G; Ragazzoni, A; Pallanti, S;
Indirizzi:
IRCCS S Lucia, Rome, Italy IRCCS S Lucia Rome ItalyIRCCS S Lucia, Rome, Italy Inst Neurosci, I-50137 Florence, Italy Inst Neurosci Florence Italy I-50137 t Neurosci, I-50137 Florence, Italy Florence Hlth Care Serv, Clin Neurophysiol Unit, Florence, Italy Florence Hlth Care Serv Florence Italy urophysiol Unit, Florence, Italy
Titolo Testata:
JOURNAL OF PSYCHIATRIC RESEARCH
fascicolo: 1, volume: 34, anno: 2000,
pagine: 75 - 82
SICI:
0022-3956(200001/02)34:1<75:AVEPIO>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
COGNITIVE DEFICITS; P300; INHIBITION; ERP; DISCRIMINATION; TOMOGRAPHY; COMPONENT; TASKS; SCALE; TESTS;
Keywords:
OCD; comorbidity; P3; cognitive functions; evoked potentials; DRT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Clinical Medicine
Life Sciences
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Pallanti, S Inst Neurosci, Vle Ugo Bassi 1, I-50137 Florence, Italy Inst Neurosci Vle Ugo Bassi 1 Florence Italy I-50137 e, Italy
Citazione:
F. Di Russo et al., "Abnormal visual event-related potentials in obsessive-compulsive disorder without panic disorder or depression comorbidity", J PSYCH RES, 34(1), 2000, pp. 75-82

Abstract

Visual event-related potentials and spline map topography during a discriminative response task (DRT) were studied in 8 obsessive-compulsive disorder(OCD) patients without comorbidity for panic disorder or depression and in12 age-matched controls. In the DRT task (like in a go/no-go task) the subject had to press a button when the target stimuli appeared and had to retain the response when the non-target stimulus appeared (vertical bars were intermixed with an equal probability of horizontals), OC patients had greater N1 latency than controls and their N1 and P3 amplitude was larger for thetarget stimuli, but not for non-target stimuli. In the normals, non-targetstimuli (no-go task) produced a larger activation than target stimuli (go task). In the OCD patients the target stimuli produced the same large activation as the non-target. These findings are consistent with theories that consider OCD to be an attentional disorder deriving from a misallocaling of cognitive resources. Moreover, spline map topography confirmed that P3 hyperactivation is localised principally on the frontal lobes. (C) 2000 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/01/20 alle ore 07:21:04