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Titolo:
An instrumental study of the relationship between extrapyramidal signs andpsychosis in Alzheimer's disease
Autore:
Caligiuri, MP; Peavy, G;
Indirizzi:
Univ Calif San Diego, Dept Psychiat 0603, Movement Disorders Lab, La Jolla, CA 92053 USA Univ Calif San Diego La Jolla CA USA 92053 rs Lab, La Jolla, CA 92053 USA Univ Calif San Diego, Dept Neurosci, La Jolla, CA 92053 USA Univ Calif SanDiego La Jolla CA USA 92053 urosci, La Jolla, CA 92053 USA
Titolo Testata:
JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES
fascicolo: 1, volume: 12, anno: 2000,
pagine: 34 - 39
SICI:
0895-0172(200024)12:1<34:AISOTR>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
COGNITIVE DETERIORATION; BEHAVIORAL SYMPTOMS; MOTOR SIGNS; PREDICTORS; DELUSIONS; DEMENTIA; DISORDERS; CIRCUITS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
42
Recensione:
Indirizzi per estratti:
Indirizzo: Caligiuri, MP Univ Calif San Diego, Dept Psychiat 0603, Movement DisordersLab, La Jolla, CA 92053 USA Univ Calif San Diego La Jolla CA USA 92053 la, CA 92053 USA
Citazione:
M.P. Caligiuri e G. Peavy, "An instrumental study of the relationship between extrapyramidal signs andpsychosis in Alzheimer's disease", J NEUROP CL, 12(1), 2000, pp. 34-39

Abstract

Neurobehavioral disturbances often coexist with extrapyramidal signs (EPS)in patients with Alzheimer's disease (AD). In the present study, we examined the PL relationships between delusions and hallucinations and EPS by using standard observer ratings and sensitive electromyographic (EMG) measuresin 52 patients with probable AD. On the basis of observer ratings, 36.5% of the patients exhibited psychotic features and 63.5% exhibited parkinsonism. Severity of clinically rated parkinsonism and the EMG measure of bradykinesia were significantly correlated with severity of neurobehavioral disturbances in this sample. The association between parkinsonism and delusions and hallucinations suggests a subcortical mechanism in the etiopathology of psychosis in AD.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 09:43:32