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Titolo:
Intravenous Optison (R) (FS069) enhances pulmonary vein flow velocity signals: A multicenter study
Autore:
Ellahham, S; Hausnerova, E; Gottdiener, J;
Indirizzi:
Washington Hosp Ctr, Div Cardiol, Washington, DC 20010 USA Washington HospCtr Washington DC USA 20010 iol, Washington, DC 20010 USA Georgetown Univ, Med Ctr, Div Cardiol, Washington, DC 20007 USA GeorgetownUniv Washington DC USA 20007 Cardiol, Washington, DC 20007 USA
Titolo Testata:
CLINICAL CARDIOLOGY
fascicolo: 2, volume: 23, anno: 2000,
pagine: 91 - 95
SICI:
0160-9289(200002)23:2<91:IO((EP>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
MYOCARDIAL CONTRAST ECHOCARDIOGRAPHY; SONICATED ALBUMIN; DOPPLER SIGNAL; AGENT; INJECTION; STENOSIS;
Keywords:
Optison (R); ultrasound contrast; Doppler signals; echocardiography; velocity flow;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
17
Recensione:
Indirizzi per estratti:
Indirizzo: Ellahham, S Washington Hosp Ctr, Div Cardiol, Room 1103,110 Irving St NW, Washington, DC 20010 USA Washington Hosp Ctr Room 1103,110 Irving St NW Washington DC USA 20010
Citazione:
S. Ellahham et al., "Intravenous Optison (R) (FS069) enhances pulmonary vein flow velocity signals: A multicenter study", CLIN CARD, 23(2), 2000, pp. 91-95

Abstract

Background: Pulmonary vein spectral Doppler signals to characterize ventricular diastolic and systolic function, though often difficult to obtain, can be enhanced using contrast agents. Hypothesis: The objective of this study was to determine the efficacy of the intravenous contrast agent Optison(R) for enhancement of Doppler signalsin patients with poor signals on two-dimensional echocardiographic examinations. Methods: Enhancement of pulmonary venous now was evaluated in 191 patientsat 0.2, 0.5, 3.0, and 5.0 ml per injection. Results: Greatest contrast enhancement for right and left pulmonary veins was observed at the highest doses. At 0.5 ml, conversion from inadequate toadequate was observed in right and left pulmonary veins in 48.0 and 79.3% of patients, respectively, while any degree of improvement was 54.4 and 65.8%. respectively. The adverse event rate (6.5%) was similar to a first-generation agent. Conclusion. The results demonstrate that Optison is a safe and effective contrast agent for improving visualization of pulmonary Doppler signals, especially the left pulmonary vein.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 03:49:13