Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Cytochrome P450-mediated drug interactions
Autore:
Flockhart, DA; Oesterheld, JR;
Indirizzi:
Georgetown Univ, Med Ctr, Dept Med, Washington, DC 20007 USA Georgetown Univ Washington DC USA 20007 ept Med, Washington, DC 20007 USA Georgetown Univ, Med Ctr, Dept Pharmacol, Washington, DC 20007 USA Georgetown Univ Washington DC USA 20007 armacol, Washington, DC 20007 USA Georgetown Univ, Med Ctr, Pharmacogenet Core Lab, Div Clin Pharmacol, Washington, DC 20007 USA Georgetown Univ Washington DC USA 20007 armacol, Washington, DC 20007 USA Univ S Dakota, Sch Med, Dept Psychiat, Div Child Psychiat, Sioux Falls, SDUSA Univ S Dakota Sioux Falls SD USA Div Child Psychiat, Sioux Falls, SDUSA
Titolo Testata:
CHILD AND ADOLESCENT PSYCHIATRIC CLINICS OF NORTH AMERICA
fascicolo: 1, volume: 9, anno: 2000,
pagine: 43 -
SICI:
1056-4993(200001)9:1<43:CPDI>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN LIVER-MICROSOMES; SEROTONIN REUPTAKE INHIBITORS; CYP2D6 GENE DUPLICATION; HYDROXYLATION IN-VITRO; TORSADES-DE-POINTES; S-MEPHENYTOIN; PHARMACOKINETIC INTERACTIONS; ANTIEPILEPTIC DRUGS; POOR METABOLIZERS; STEREOSELECTIVE METABOLISM;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Citazioni:
185
Recensione:
Indirizzi per estratti:
Indirizzo: Oesterheld, JR 2812 S Louise Ave, Sioux Falls, SD 57105 USA 2812 S LouiseAve Sioux Falls SD USA 57105 s, SD 57105 USA
Citazione:
D.A. Flockhart e J.R. Oesterheld, "Cytochrome P450-mediated drug interactions", CH ADOLESC, 9(1), 2000, pp. 43

Abstract

This article reviews hepatic P450-drug-metabolizing cytochromes (CYPs). Starting with the nomenclature and development of CYPs, the authors discuss concepts necessary to understand clinically relevant CYP-based drug interactions, polymorphisms, substrates, inhibitors, and inducers of CYP1A2, CYP2C9, CYP2C19, CYP2D6, CYP2E1, and the CYP3A subfamily are reviewed. Case histories, CYP lists, and CYP websites are provided to highlight drug interactions relevant to child psychiatrists.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 16:24:45