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Titolo:
Patterns of neuroleptic drug prescription: a national cross-sectional survey of a random sample of French psychiatrists
Autore:
Fourrier, A; Gasquet, I; Allicar, MP; Bouhassira, M; Lepine, JP; Begaud, B;
Indirizzi:
Univ Bordeaux 2, Dept Pharmacol, F-33076 Bordeaux, France Univ Bordeaux 2Bordeaux France F-33076 rmacol, F-33076 Bordeaux, France Hop Paul Brousse, Dept Publ Hlth, Villejuif, France Hop Paul Brousse Villejuif France se, Dept Publ Hlth, Villejuif, France Lilly France, St Cloud, France Lilly France St Cloud FranceLilly France, St Cloud, France Hop Fernand Widal, Dept Psychiat, Paris, France Hop Fernand Widal Paris France nand Widal, Dept Psychiat, Paris, France
Titolo Testata:
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
fascicolo: 1, volume: 49, anno: 2000,
pagine: 80 - 86
SICI:
0306-5251(200001)49:1<80:PONDPA>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Keywords:
antipsychotic drugs; cross-sectional study; drug utilization study; France; pharmacoepidemiology;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
10
Recensione:
Indirizzi per estratti:
Indirizzo: Fourrier, A Univ Bordeaux 2, Dept Pharmacol, F-33076 Bordeaux, France UnivBordeaux 2 Bordeaux France F-33076 076 Bordeaux, France
Citazione:
A. Fourrier et al., "Patterns of neuroleptic drug prescription: a national cross-sectional survey of a random sample of French psychiatrists", BR J CL PH, 49(1), 2000, pp. 80-86

Abstract

Aims To describe the psychiatric indications of neuroleptics (especially the relative share of schizophrenic and other psychotic disorders) and the usage patterns of these drugs (dose, duration, coprescriptions). Methods A one-day national cross-sectional survey in a random sample of 723 French psychiatrists was carried out in 1996. Each psychiatrist was askedto complete a standardized questionnaire for the first three patients seenthe day of the survey to whom at least one neuroleptic was prescribed (initiated or renewed). Results One thousand seven hundred and fifty-four questionnaires were returned. Three quarters of the patients (74%) were psychotic (664 with schizophrenia, and 636 other psychosis), 19.3% were depressive and 6.7% had other psychiatric disorders. Phenothiazines were the most often prescribed (40.8%), followed by butyrophenones (22.5%), benzamides (15.8%), other neuroleptics (14.8%) and thioxanthenes (6.1%). Among schizophrenic subjects, an average number of 1.54 (95% CI: 1.50-1.60) neuroleptics were prescribed per patient, compared with 1.4 (95% CI: 1.32-1.41) and 1.2 (95% CI: 1.14-1.23) in other psychotic and depressive subjects, respectively. Regardless of the indication, non-neuroleptic psychotropic drugs were coprescribed in 75.4%, mainly benzodiazepines (75.7%). Adjuvant drugs used in prevention or treatmentof side-effects were coprescribed in 46.7%, mostly anticholinergic antiparkinsonians (86.1%). Conclusions Neuroleptics are mainly prescribed for psychotic disorders andespecially schizophrenia. However, current recommendations are not always followed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 06:39:35