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Titolo:
A silent event-related functional MRI technique for brain activation studies without interference of scanner acoustic noise
Autore:
Yang, YH; Engelien, A; Engelien, W; Xu, S; Stern, E; Silbersweig, DA;
Indirizzi:
Cornell Univ, Weill Med Coll, Dept Psychiat, Funct Neuroimaging Lab, New York, NY 10021 USA Cornell Univ New York NY USA 10021 uroimaging Lab, New York, NY 10021 USA Mem Sloan Kettering Canc Ctr, Dept Med Phys, New York, NY 10021 USA Mem Sloan Kettering Canc Ctr New York NY USA 10021 New York, NY 10021 USA
Titolo Testata:
MAGNETIC RESONANCE IN MEDICINE
fascicolo: 2, volume: 43, anno: 2000,
pagine: 185 - 190
SICI:
0740-3194(200002)43:2<185:ASEFMT>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN AUDITORY-CORTEX; CORTICAL ACTIVATION; FMRI; SYSTEMS;
Keywords:
functional MRI; brain hemodynamic response; auditory tonotopic mapping; scanner acoustic noise;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Yang, YH Cornell Univ, Weill Med Coll, Dept Psychiat, Funct Neuroimaging Lab, 525 E68th St,Box 140,Room F1306, New York, NY 10021 USA Cornell Univ 525 E 68th St,Box 140,Room F1306 New York NY USA 10021
Citazione:
Y.H. Yang et al., "A silent event-related functional MRI technique for brain activation studies without interference of scanner acoustic noise", MAGN RES M, 43(2), 2000, pp. 185-190

Abstract

A new data acquisition method for silent, event-related functional MRI in which scanner acoustic noise does not interfere with brain activation is introduced and evaluated in an auditory tonotopic mapping experiment. This method takes into account the hemodynamic-response characteristics of the brain during activation, associated with both task performance and scanner noise. A data acquisition scheme was designed to collect task-induced brain activation signals without interference of scanner noise on stimulus deliveryor on the measured response. The advantages of the technique were demonstrated in a tonotopic mapping experiment of human auditory cortex. Tonotopic maps obtained by the technique in normal subjects showed distinct spatial shifts of the activation fool in the lateral part of Heschl's gyrus with changing stimulus frequency, whereas no systematic shift was shown in a conventional event-related experiment using the same stimulation paradigm. Signalchange in the activation foci with the new technique was 54% larger than with the conventional technique, suggesting an increased dynamic range of the signal change associated with task-induced brain activation under silent conditions. (C) 2000 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 07:20:30