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Titolo:
Blood pressure and menopausal transition: the Atherosclerosis Risk in Communities study (1987-95)
Autore:
Luoto, R; Sharrett, AR; Schreiner, P; Sorlie, PD; Arnett, D; Ephross, S;
Indirizzi:
Natl Publ Hlth Inst, Dept Hlth & Disabil, FIN-00300 Helsinki, Finland NatlPubl Hlth Inst Helsinki Finland FIN-00300 N-00300 Helsinki, Finland NHLBI, NIH, Bethesda, MD 20892 USA NHLBI Bethesda MD USA 20892NHLBI, NIH, Bethesda, MD 20892 USA Univ Minnesota, Div Epidemiol, Minneapolis, MN 55455 USA Univ Minnesota Minneapolis MN USA 55455 demiol, Minneapolis, MN 55455 USA Univ N Carolina, Dept Epidemiol, Chapel Hill, NC USA Univ N Carolina Chapel Hill NC USA , Dept Epidemiol, Chapel Hill, NC USA Glaxo Wellcome Inc, Worldwide Epidemiol, Res Triangle Pk, NC 27709 USA Glaxo Wellcome Inc Res Triangle Pk NC USA 27709 Triangle Pk, NC 27709 USA
Titolo Testata:
JOURNAL OF HYPERTENSION
fascicolo: 1, volume: 18, anno: 2000,
pagine: 27 - 33
SICI:
0263-6352(200001)18:1<27:BPAMTT>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEART-DISEASE; WOMEN; HYSTERECTOMY; FRAMINGHAM; POPULATION; WEIGHT; AGE;
Keywords:
menopause; blood pressure; hypertension; weight change; ethnicity;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Luoto, R Natl Publ Hlth Inst, Dept Hlth & Disabil, Mannerheimintie 166, FIN-00300 Helsinki, Finland Natl Publ Hlth Inst Mannerheimintie 166 HelsinkiFinland FIN-00300
Citazione:
R. Luoto et al., "Blood pressure and menopausal transition: the Atherosclerosis Risk in Communities study (1987-95)", J HYPERTENS, 18(1), 2000, pp. 27-33

Abstract

Objective Blood pressure changes during menopausal transition have not been studied previously using a biracial sample. We invesigated whether menopausal transition was associated with change in blood pressure in African-American or white women. Design, setting and participants The prospective multicenter study, the Atherosclerosis Risk In Communities (ARIC) Study (1987-95) was utilized. Included were never-users of hormone replacement therapy (3800 women, 44% of the original sample). Main outcome measure Changes in blood pressure were adjusted for baseline age and body mass index, baseline blood pressure, antihypertensive use, ARIC field center and weight change. The menopausal transition group was compared to the non-transition group, separately, by ethnicity,Results Women undergoing the menopausal transition did not differ significantly in regard to systolic blood pressure change [5.2, 95% confidence interval (CI) 4.0- 6.4] from non-transitional women (4.6, 95% CI 4.0-5.2); adjustment for age, baseline systolic blood pressure and other factors did not alter this finding. Transitional women had significantly less diastolic blood pressure change (-0.5, 95% CI -1.1 to 0.2) than non-transitional women (-2.0, 95% CI -2.4 to -1.7, P = 0.000) but, after adjustment for other covariates, the result was not significant. African-American women had significantly (P = 0.003) higher systolic blood pressure change compared to white women, but this difference became non-significant (P = 0.21) after restricting the sample to women younger than 55 years of age. Interactions between menopausal transition and ethnicity were not significant, either in systolic blood pressure or diastolic blood pressure change. Conclusion Menopausal transition is not associated with significant blood pressure change in African-American or white women. J Hypertens 2000, 18:27-33 (C) Lippincott Williams & Wilkins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 15:22:56