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Titolo:
On-line set-up corrections during radiotherapy of patients with gynecologic tumors
Autore:
Stroom, JC; Olofsen-van Acht, MJJ; Quint, S; Seven, M; De Hoog, M; Creutzberg, CL; De Boer, HCJ; Visser, AG;
Indirizzi:
Univ Rotterdam Hosp, Dr Daniel Den Hoed Canc Ctr, Dept Radiat Oncol, Div Clin Phys & Instrumentat, NL-3075 EA Rotterdam, Netherlands Univ Rotterdam Hosp Rotterdam Netherlands NL-3075 EA terdam, Netherlands
Titolo Testata:
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
fascicolo: 2, volume: 46, anno: 2000,
pagine: 499 - 506
SICI:
0360-3016(20000115)46:2<499:OSCDRO>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
IMAGING-SYSTEM; PORTAL IMAGES; VERIFICATION PROCEDURE; IRRADIATION; RADIATION; ACCURACY; CANCER;
Keywords:
on-line set-up correction; off-line set-up correction; set-up deviation; CTV-to-PTV margin; gynecologic tumors;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Stroom, JC Univ Rotterdam Hosp, Dr Daniel Den Hoed Canc Ctr, Dept Radiat Oncol, Div Clin Phys & Instrumentat, Groene Hilledijk 301, NL-3075 EA Rotterdam, Netherlands Univ Rotterdam Hosp Groene Hilledijk 301 Rotterdam Netherlands NL-3075 EA
Citazione:
J.C. Stroom et al., "On-line set-up corrections during radiotherapy of patients with gynecologic tumors", INT J RAD O, 46(2), 2000, pp. 499-506

Abstract

Purpose: Positioning of patients with gynecologic tumors for radiotherapy has proven to be relatively inaccurate. To improve the accuracy and reduce the margins from clinical target volume (CTV) to planning target volume (PTV), on-line set-up corrections were investigated. Methods and Materials: Anterior-posterior portal images of 14 patients were acquired using the first six monitor units (MU) of each irradiation fraction, The set-up deviation was established by matching three user-defined landmarks in portal and simulator image. If the two-dimensional deviation exceeded 4 mm, the table position was corrected. A second portal image was acquired using 30 MU of the remaining dose. This image was analyzed off-line using a semiautomatic contour match to obtain the final set-up accuracy. To verify the landmark match accuracy, the contour match was retrospectively performed on the six MU images as well. Results: The standard deviation (SD) of the distribution of systematic set-up deviations after correction was < 1 mm in left-right and cranio-caudal directions. The average random deviation was < 2 mm in these directions (1 SD). Before correction, all standard deviations were 2 to 3 mm, The landmark match procedure was sufficiently accurate and added on average 3 min to the treatment time. The application of on-line corrections justifies a CTV-to-PTV margin reduction to about 5 mm. Conclusions: On-line set-up corrections significantly improve the positioning accuracy. The procedure increases treatment time but might be used effectively in combination with off-line corrections. (C) 2000 Elsevier ScienceInc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 08/08/20 alle ore 08:56:14