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Titolo:
Sonography, CT, and MR imaging: A prospective comparison of neonates with suspected intracranial ischemia and hemorrhage
Autore:
Blankenberg, FG; Loh, NN; Bracci, P; DArceuil, HE; Rhine, WD; Norbash, AM; Lane, B; Berg, A; Person, B; Coutant, M; Enzmann, DR;
Indirizzi:
Stanford Univ, Sch Med, Dept Radiol, Stanford, CA 94305 USA Stanford UnivStanford CA USA 94305 , Dept Radiol, Stanford, CA 94305 USA Lucile Salter Packard Childrens Hosp, Dept Pediat, Palo Alto, CA USA Lucile Salter Packard Childrens Hosp Palo Alto CA USA Palo Alto, CA USA Lucile Salter Packard Childrens Hosp, Dept Neonatal Med, Palo Alto, CA USALucile Salter Packard Childrens Hosp Palo Alto CA USA Palo Alto, CA USA Lucile Salter Packard Childrens Hosp, Dept Pediat Radiol, Palo Alto, CA USA Lucile Salter Packard Childrens Hosp Palo Alto CA USA Palo Alto, CA USA Univ Calif San Francisco, Dept Epidemiol & Biostat, San Francisco, CA 94143 USA Univ Calif San Francisco San Francisco CA USA 94143 ancisco, CA 94143 USA
Titolo Testata:
AMERICAN JOURNAL OF NEURORADIOLOGY
fascicolo: 1, volume: 21, anno: 2000,
pagine: 213 - 218
SICI:
0195-6108(200001)21:1<213:SCAMIA>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
CEREBRAL BLOOD-FLOW; CENTRAL-NERVOUS-SYSTEM; BIRTH-WEIGHT INFANTS; CRANIAL ULTRASOUND; PRETERM INFANTS; PERINATAL ASPHYXIA; PREDICTIVE VALUE; NEWBORN LAMB; ENCEPHALOPATHY; US;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Blankenberg, FG Stanford Univ, Sch Med, Dept Radiol, 300 Pasteur Dr, Stanford, CA 94305 USA Stanford Univ 300 Pasteur Dr Stanford CA USA 94305 305 USA
Citazione:
F.G. Blankenberg et al., "Sonography, CT, and MR imaging: A prospective comparison of neonates with suspected intracranial ischemia and hemorrhage", AM J NEUROR, 21(1), 2000, pp. 213-218

Abstract

BACKGROUND AND PURPOSE: Sonography, CT, and MR imaging are commonly used to screen for neonatal intracranial ischemia and hemorrhage, yet few studieshave attempted to determine which imaging technique is best suited for this purpose. The goals of this study were to compare sonography with CT and MR imaging prospectively for the detection of intracranial ischemia or hemorrhage and to determine the prognostic value(s) of neuroimaging in neonates suspected of having hypoxic-ischemic injury (HII). METHODS: Forty-seven neonates underwent CT (n = 26) or MR imaging (n = 24)or both (n = 3) within the first month of life for suspected HII. Sonography was performed according to research protocol within an average of 14.4 +/- 9.6 hours of CT or MR imaging. A kappa analysis of interobserver agreement was conducted using three independent observers. Infants underwent neurodevelopmental assessment at ages 2 months (n = 47) and 2 years (n = 26). RESULTS: CT and MR imaging had significantly higher interobserver agreement (P < .001) for cortical HII and germinal matrix hemorrhage (GMH) (Grades I and II) compared with sonography, MR imaging and CT revealed 25 instancesof HII compared with 13 identified by sonography, MR imaging and CT also revealed 10 instances of intraparenchymal hemorrhage (>1 cm, including GradeIV GMH) compared with sonography, which depicted five. The negative predictive values of neuroimaging, irrespective of technique used, were 53.3% and58.8% at the 2-month and 2-year follow-up examinations, respectively. CONCLUSION: CT and MR imaging have significantly better interobserver agreement for cortical HII and GMH/intraventricular hemorrhage and can reveal more instances of intraparenchymal hemorrhage compared with sonography. The absence of neuroimaging findings on sonograms, CT scans, or MR images does not rule out later neurologic dysfunction.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/07/20 alle ore 09:33:37